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TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures.
Chaurio RA, Anadon CM, Lee Costich T, Payne KK, Biswas S, Harro CM, Moran C, Ortiz AC, Cortina C, Rigolizzo KE, Sprenger KB, Mine JA, Innamarato P, Mandal G, Powers JJ, Martin A, Wang Z, Mehta S, Perez BA, Li R, Robinson J, Kroeger JL, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR. Chaurio RA, et al. Immunity. 2022 Jan 11;55(1):115-128.e9. doi: 10.1016/j.immuni.2021.12.007. Immunity. 2022. PMID: 35021053 Free PMC article.
SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells.
Stephen TL, Payne KK, Chaurio RA, Allegrezza MJ, Zhu H, Perez-Sanz J, Perales-Puchalt A, Nguyen JM, Vara-Ailor AE, Eruslanov EB, Borowsky ME, Zhang R, Laufer TM, Conejo-Garcia JR. Stephen TL, et al. Among authors: chaurio ra. Immunity. 2017 Jan 17;46(1):51-64. doi: 10.1016/j.immuni.2016.12.015. Immunity. 2017. PMID: 28099864 Free PMC article.
Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice.
Harro CM, Perez-Sanz J, Costich TL, Payne KK, Anadon CM, Chaurio RA, Biswas S, Mandal G, Rigolizzo KE, Sprenger KB, Mine JA, Showe LC, Yu X, Liu K, Rodriguez PC, Pinilla-Ibarz J, Sokol L, Conejo-Garcia JR. Harro CM, et al. Among authors: chaurio ra. J Clin Invest. 2021 Feb 1;131(3):e135711. doi: 10.1172/JCI135711. J Clin Invest. 2021. PMID: 33270606 Free PMC article.
Humoral immune responses: Unsung heroes of the war on cancer.
Conejo-Garcia JR, Biswas S, Chaurio R. Conejo-Garcia JR, et al. Semin Immunol. 2020 Jun;49:101419. doi: 10.1016/j.smim.2020.101419. Epub 2020 Nov 9. Semin Immunol. 2020. PMID: 33183950 Free PMC article. Review.
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells.
Payne KK, Mine JA, Biswas S, Chaurio RA, Perales-Puchalt A, Anadon CM, Costich TL, Harro CM, Walrath J, Ming Q, Tcyganov E, Buras AL, Rigolizzo KE, Mandal G, Lajoie J, Ophir M, Tchou J, Marchion D, Luca VC, Bobrowicz P, McLaughlin B, Eskiocak U, Schmidt M, Cubillos-Ruiz JR, Rodriguez PC, Gabrilovich DI, Conejo-Garcia JR. Payne KK, et al. Among authors: chaurio ra. Science. 2020 Aug 21;369(6506):942-949. doi: 10.1126/science.aay2767. Science. 2020. PMID: 32820120 Free PMC article.
Olfactory Receptor OR2H1 Is an Effective Target for CAR T Cells in Human Epithelial Tumors.
Martin AL, Anadon CM, Biswas S, Mine JA, Handley KF, Payne KK, Mandal G, Chaurio RA, Powers JJ, Sprenger KB, Rigolizzo KE, Innamarato P, Harro CM, Mehta S, Perez BA, Wenham RM, Conejo-Garcia JR. Martin AL, et al. Among authors: chaurio ra. Mol Cancer Ther. 2022 Jul 5;21(7):1184-1194. doi: 10.1158/1535-7163.MCT-21-0872. Mol Cancer Ther. 2022. PMID: 35499393 Free PMC article.
IgA transcytosis and antigen recognition govern ovarian cancer immunity.
Biswas S, Mandal G, Payne KK, Anadon CM, Gatenbee CD, Chaurio RA, Costich TL, Moran C, Harro CM, Rigolizzo KE, Mine JA, Trillo-Tinoco J, Sasamoto N, Terry KL, Marchion D, Buras A, Wenham RM, Yu X, Townsend MK, Tworoger SS, Rodriguez PC, Anderson AR, Conejo-Garcia JR. Biswas S, et al. Among authors: chaurio ra. Nature. 2021 Mar;591(7850):464-470. doi: 10.1038/s41586-020-03144-0. Epub 2021 Feb 3. Nature. 2021. PMID: 33536615 Free PMC article.
IgA-Dominated Humoral Immune Responses Govern Patients' Outcome in Endometrial Cancer.
Mandal G, Biswas S, Anadon CM, Yu X, Gatenbee CD, Prabhakaran S, Payne KK, Chaurio RA, Martin A, Innamarato P, Moran C, Powers JJ, Harro CM, Mine JA, Sprenger KB, Rigolizzo KE, Wang X, Curiel TJ, Rodriguez PC, Anderson AR, Saglam O, Conejo-Garcia JR. Mandal G, et al. Among authors: chaurio ra. Cancer Res. 2022 Mar 1;82(5):859-871. doi: 10.1158/0008-5472.CAN-21-2376. Cancer Res. 2022. PMID: 34949671 Free PMC article.
Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells.
Anadon CM, Yu X, Hänggi K, Biswas S, Chaurio RA, Martin A, Payne KK, Mandal G, Innamarato P, Harro CM, Mine JA, Sprenger KB, Cortina C, Powers JJ, Costich TL, Perez BA, Gatenbee CD, Prabhakaran S, Marchion D, Heemskerk MHM, Curiel TJ, Anderson AR, Wenham RM, Rodriguez PC, Conejo-Garcia JR. Anadon CM, et al. Among authors: chaurio ra. Cancer Cell. 2022 May 9;40(5):545-557.e13. doi: 10.1016/j.ccell.2022.03.008. Epub 2022 Apr 14. Cancer Cell. 2022. PMID: 35427494 Free PMC article.
Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy.
Perales-Puchalt A, Perez-Sanz J, Payne KK, Svoronos N, Allegrezza MJ, Chaurio RA, Anadon C, Calmette J, Biswas S, Mine JA, Costich TL, Nickels L, Wickramasinghe J, Rutkowski MR, Conejo-Garcia JR. Perales-Puchalt A, et al. Among authors: chaurio ra. J Leukoc Biol. 2018 May;103(5):799-805. doi: 10.1002/JLB.5HI1117-446RR. Epub 2018 Mar 14. J Leukoc Biol. 2018. PMID: 29537705 Free PMC article.
37 results