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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1969 1
1972 1
1973 1
1975 2
1976 1
1979 1
1987 1
1988 3
1989 2
1990 4
1991 2
1992 2
1993 3
1995 5
1996 1
1997 2
1999 3
2000 1
2001 3
2002 1
2003 2
2004 2
2005 3
2006 5
2007 6
2008 2
2009 9
2010 5
2011 5
2012 5
2013 10
2014 5
2015 7
2016 4
2017 8
2018 2
2019 4
2020 5
2021 11
2022 12
2023 8
2024 5

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150 results

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Page 1
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Logan T, Simon MJ, Rana A, Cherf GM, Srivastava A, Davis SS, Low RLY, Chiu CL, Fang M, Huang F, Bhalla A, Llapashtica C, Prorok R, Pizzo ME, Calvert MEK, Sun EW, Hsiao-Nakamoto J, Rajendra Y, Lexa KW, Srivastava DB, van Lengerich B, Wang J, Robles-Colmenares Y, Kim DJ, Duque J, Lenser M, Earr TK, Nguyen H, Chau R, Tsogtbaatar B, Ravi R, Skuja LL, Solanoy H, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Dennis MS, Kariolis MS, Monroe KM, Przybyla L, Sanchez PE, Meisner R, Diaz D, Henne KR, Watts RJ, Henry AG, Gunasekaran K, Astarita G, Suh JH, Lewcock JW, DeVos SL, Di Paolo G. Logan T, et al. Among authors: chau r. Cell. 2021 Sep 2;184(18):4651-4668.e25. doi: 10.1016/j.cell.2021.08.002. Epub 2021 Aug 26. Cell. 2021. PMID: 34450028 Free PMC article.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK, Lin CC, Davis S, Ha C, Leung AW, Nguyen H, Chau R, Yulyaningsih E, Lopez I, Solanoy H, Masoud ST, Liang CC, Lin K, Astarita G, Khoury N, Zuchero JY, Thorne RG, Shen K, Miller S, Palop JJ, Garceau D, Sasner M, Whitesell JD, Harris JA, Hummel S, Gnörich J, Wind K, Kunze L, Zatcepin A, Brendel M, Willem M, Haass C, Barnett D, Zimmer TS, Orr AG, Scearce-Levie K, Lewcock JW, Di Paolo G, Sanchez PE. Xia D, et al. Among authors: chau r. Mol Neurodegener. 2022 Jun 11;17(1):41. doi: 10.1186/s13024-022-00547-7. Mol Neurodegener. 2022. PMID: 35690868 Free PMC article.
Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme.
Arguello A, Mahon CS, Calvert MEK, Chan D, Dugas JC, Pizzo ME, Thomsen ER, Chau R, Damo LA, Duque J, Fang M, Giese T, Kim DJ, Liang N, Nguyen HN, Solanoy H, Tsogtbaatar B, Ullman JC, Wang J, Dennis MS, Diaz D, Gunasekaran K, Henne KR, Lewcock JW, Sanchez PE, Troyer MD, Harris JM, Scearce-Levie K, Shan L, Watts RJ, Thorne RG, Henry AG, Kariolis MS. Arguello A, et al. Among authors: chau r. J Exp Med. 2022 Mar 7;219(3):e20211057. doi: 10.1084/jem.20211057. Epub 2022 Feb 28. J Exp Med. 2022. PMID: 35226042 Free PMC article.
On the origins and biosynthesis of tetrodotoxin.
Chau R, Kalaitzis JA, Neilan BA. Chau R, et al. Aquat Toxicol. 2011 Jul;104(1-2):61-72. doi: 10.1016/j.aquatox.2011.04.001. Epub 2011 Apr 8. Aquat Toxicol. 2011. PMID: 21543051 Review.
Biosynthesis of toxic naturally-occurring seafood contaminants.
Kalaitzis JA, Chau R, Kohli GS, Murray SA, Neilan BA. Kalaitzis JA, et al. Among authors: chau r. Toxicon. 2010 Aug 15;56(2):244-58. doi: 10.1016/j.toxicon.2009.09.001. Epub 2009 Sep 15. Toxicon. 2010. PMID: 19761784 Review.
A Pseudoalteromonas Clade with Remarkable Biosynthetic Potential.
Chau R, Pearson LA, Cain J, Kalaitzis JA, Neilan BA. Chau R, et al. Appl Environ Microbiol. 2021 Feb 26;87(6):e02604-20. doi: 10.1128/AEM.02604-20. Print 2021 Feb 26. Appl Environ Microbiol. 2021. PMID: 33397702 Free PMC article.
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors.
Keylor MH, Gulati A, Kattar SD, Johnson RE, Chau RW, Margrey KA, Ardolino MJ, Zarate C, Poremba KE, Simov V, Morriello GJ, Acton JJ, Pio B, Yan X, Palte RL, McMinn SE, Nogle L, Lesburg CA, Adpressa D, Lin S, Neelamkavil S, Liu P, Su J, Hegde LG, Woodhouse JD, Faltus R, Xiong T, Ciaccio PJ, Piesvaux J, Otte KM, Wood HB, Kennedy ME, Bennett DJ, DiMauro EF, Fell MJ, Fuller PH. Keylor MH, et al. Among authors: chau rw. J Med Chem. 2022 Jan 13;65(1):838-856. doi: 10.1021/acs.jmedchem.1c01968. Epub 2021 Dec 30. J Med Chem. 2022. PMID: 34967623
150 results