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Page 1
Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Parmenopoulou V, Chatzileontiadou DS, Manta S, Bougiatioti S, Maragozidis P, Gkaragkouni DN, Kaffesaki E, Kantsadi AL, Skamnaki VT, Zographos SE, Zounpoulakis P, Balatsos NA, Komiotis D, Leonidas DD. Parmenopoulou V, et al. Among authors: chatzileontiadou ds. Bioorg Med Chem. 2012 Dec 15;20(24):7184-93. doi: 10.1016/j.bmc.2012.09.067. Epub 2012 Oct 16. Bioorg Med Chem. 2012. PMID: 23122937
Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase.
Kantsadi AL, Apostolou A, Theofanous S, Stravodimos GA, Kyriakis E, Gorgogietas VA, Chatzileontiadou DS, Pegiou K, Skamnaki VT, Stagos D, Kouretas D, Psarra AM, Haroutounian SA, Leonidas DD. Kantsadi AL, et al. Among authors: chatzileontiadou ds. Food Chem Toxicol. 2014 May;67:35-43. doi: 10.1016/j.fct.2014.01.055. Epub 2014 Feb 18. Food Chem Toxicol. 2014. PMID: 24556570
Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines.
Parmenopoulou V, Kantsadi AL, Tsirkone VG, Chatzileontiadou DS, Manta S, Zographos SE, Molfeta C, Archontis G, Agius L, Hayes JM, Leonidas DD, Komiotis D. Parmenopoulou V, et al. Among authors: chatzileontiadou ds. Bioorg Med Chem. 2014 Sep 1;22(17):4810-25. doi: 10.1016/j.bmc.2014.06.058. Epub 2014 Jul 16. Bioorg Med Chem. 2014. PMID: 25092521
Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N´-(β-D-glucopyranosyl) urea inhibitors.
Kantsadi AL, Parmenopoulou V, Bakalov DN, Snelgrove L, Stravodimos GA, Chatzileontiadou DS, Manta S, Panagiotopoulou A, Hayes JM, Komiotis D, Leonidas DD. Kantsadi AL, et al. Among authors: chatzileontiadou ds. Curr Top Med Chem. 2015;15(23):2373-89. doi: 10.2174/1568026615666150619142253. Curr Top Med Chem. 2015. PMID: 26088352
Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
Kantsadi AL, Bokor É, Kun S, Stravodimos GA, Chatzileontiadou DSM, Leonidas DD, Juhász-Tóth É, Szakács A, Batta G, Docsa T, Gergely P, Somsák L. Kantsadi AL, et al. Eur J Med Chem. 2016 Nov 10;123:737-745. doi: 10.1016/j.ejmech.2016.06.049. Epub 2016 Jul 12. Eur J Med Chem. 2016. PMID: 27522507
Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase.
Stravodimos GA, Kantsadi AL, Apostolou A, Kyriakis E, Kafaski-Kanelli VN, Solovou T, Gatzona P, Liggri PGV, Theofanous S, Gorgogietas VA, Kissa A, Psachoula C, Lemonakis A, Chatzileontiadou DSM, Psarra AG, Skamnaki VT, Haroutounian SA, Leonidas DD. Stravodimos GA, et al. Curr Drug Discov Technol. 2018;15(1):41-53. doi: 10.2174/1570163814666170619091736. Curr Drug Discov Technol. 2018. PMID: 28625148
Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Kyriakis E, Solovou TGA, Kun S, Czifrák K, Szőcs B, Juhász L, Bokor É, Stravodimos GA, Kantsadi AL, Chatzileontiadou DSM, Skamnaki VT, Somsák L, Leonidas DD. Kyriakis E, et al. Bioorg Chem. 2018 Apr;77:485-493. doi: 10.1016/j.bioorg.2018.02.008. Epub 2018 Feb 12. Bioorg Chem. 2018. PMID: 29454281
28 results