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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer.
Almanza A, Mnich K, Blomme A, Robinson CM, Rodriguez-Blanco G, Kierszniowska S, McGrath EP, Le Gallo M, Pilalis E, Swinnen JV, Chatziioannou A, Chevet E, Gorman AM, Samali A. Almanza A, et al. Among authors: chatziioannou a. Nat Commun. 2022 May 6;13(1):2493. doi: 10.1038/s41467-022-30159-0. Nat Commun. 2022. PMID: 35524156 Free PMC article.
KENeV: A web-application for the automated reconstruction and visualization of the enriched metabolic and signaling super-pathways deriving from genomic experiments.
Pilalis E, Koutsandreas T, Valavanis I, Athanasiadis E, Spyrou G, Chatziioannou A. Pilalis E, et al. Among authors: chatziioannou a. Comput Struct Biotechnol J. 2015 Apr 9;13:248-55. doi: 10.1016/j.csbj.2015.03.009. eCollection 2015. Comput Struct Biotechnol J. 2015. PMID: 26925206 Free PMC article.
Dual IRE1 RNase functions dictate glioblastoma development.
Lhomond S, Avril T, Dejeans N, Voutetakis K, Doultsinos D, McMahon M, Pineau R, Obacz J, Papadodima O, Jouan F, Bourien H, Logotheti M, Jégou G, Pallares-Lupon N, Schmit K, Le Reste PJ, Etcheverry A, Mosser J, Barroso K, Vauléon E, Maurel M, Samali A, Patterson JB, Pluquet O, Hetz C, Quillien V, Chatziioannou A, Chevet E. Lhomond S, et al. Among authors: chatziioannou a. EMBO Mol Med. 2018 Mar;10(3):e7929. doi: 10.15252/emmm.201707929. EMBO Mol Med. 2018. PMID: 29311133 Free PMC article.
Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.
Rubio-Patiño C, Bossowski JP, De Donatis GM, Mondragón L, Villa E, Aira LE, Chiche J, Mhaidly R, Lebeaupin C, Marchetti S, Voutetakis K, Chatziioannou A, Castelli FA, Lamourette P, Chu-Van E, Fenaille F, Avril T, Passeron T, Patterson JB, Verhoeyen E, Bailly-Maitre B, Chevet E, Ricci JE. Rubio-Patiño C, et al. Among authors: chatziioannou a. Cell Metab. 2018 Apr 3;27(4):828-842.e7. doi: 10.1016/j.cmet.2018.02.009. Cell Metab. 2018. PMID: 29551590 Free article.
Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1.
Obiedat A, Seidel E, Mahameed M, Berhani O, Tsukerman P, Voutetakis K, Chatziioannou A, McMahon M, Avril T, Chevet E, Mandelboim O, Tirosh B. Obiedat A, et al. Among authors: chatziioannou a. FASEB J. 2019 Mar;33(3):3481-3495. doi: 10.1096/fj.201801350RR. Epub 2018 Nov 19. FASEB J. 2019. PMID: 30452881
Deletion of IRE1 or XBP1 was sufficient to promote mRNA and surface levels of MICA. Accordingly, NKG2D played a greater role in the killing of IRE1/XBP1 knockout target cells. ...Because of the importance of E2F1 and MICA in cancer progression and recognition, these observ …
Deletion of IRE1 or XBP1 was sufficient to promote mRNA and surface levels of MICA. Accordingly, NKG2D played a greater role in the k …
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.
Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, Tavernier J, Hrstka R, Dupont A, Fessart D, Delom F, Fernandez-Zapico ME, Jansen G, Eriksson LA, Thomas DY, Jerome-Majewska L, Hupp T, Chatziioannou A, Chevet E, Ogier-Denis E. Maurel M, et al. Among authors: chatziioannou a. EMBO Mol Med. 2019 Jun;11(6):e10120. doi: 10.15252/emmm.201810120. EMBO Mol Med. 2019. PMID: 31040128 Free PMC article.
297 results