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Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.
Nikolakopoulou P, Chatzigeorgiou A, Kourtzelis I, Toutouna L, Masjkur J, Arps-Forker C, Poser SW, Rozman J, Rathkolb B, Aguilar-Pimentel JA; German Mouse Clinic Consortium; Wolf E, Klingenspor M, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Tsata V, Monasor LS, Troullinaki M, Witt A, Anastasiou V, Chrousos G, Yi CX, García-Cáceres C, Tschöp MH, Bornstein SR, Androutsellis-Theotokis A. Nikolakopoulou P, et al. Among authors: chatzigeorgiou a. Sci Rep. 2018 Jul 27;8(1):11335. doi: 10.1038/s41598-018-29434-2. Sci Rep. 2018. PMID: 30054579 Free PMC article.
Lymphocytes in obesity-related adipose tissue inflammation.
Chatzigeorgiou A, Karalis KP, Bornstein SR, Chavakis T. Chatzigeorgiou A, et al. Diabetologia. 2012 Oct;55(10):2583-2592. doi: 10.1007/s00125-012-2607-0. Epub 2012 Jun 26. Diabetologia. 2012. PMID: 22733483 Review.
Characterization of the LPS-induced inflammation of the adrenal gland in mice.
Kanczkowski W, Chatzigeorgiou A, Samus M, Tran N, Zacharowski K, Chavakis T, Bornstein SR. Kanczkowski W, et al. Among authors: chatzigeorgiou a. Mol Cell Endocrinol. 2013 May 22;371(1-2):228-35. doi: 10.1016/j.mce.2012.12.020. Epub 2013 Jan 5. Mol Cell Endocrinol. 2013. PMID: 23295830
The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance.
Phieler J, Chung KJ, Chatzigeorgiou A, Klotzsche-von Ameln A, Garcia-Martin R, Sprott D, Moisidou M, Tzanavari T, Ludwig B, Baraban E, Ehrhart-Bornstein M, Bornstein SR, Mziaut H, Solimena M, Karalis KP, Economopoulou M, Lambris JD, Chavakis T. Phieler J, et al. Among authors: chatzigeorgiou a. J Immunol. 2013 Oct 15;191(8):4367-74. doi: 10.4049/jimmunol.1300038. Epub 2013 Sep 16. J Immunol. 2013. PMID: 24043887 Free PMC article.
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Chatzigeorgiou A, et al. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24492375 Free PMC article.
Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation.
Chatzigeorgiou A, Chung KJ, Garcia-Martin R, Alexaki VI, Klotzsche-von Ameln A, Phieler J, Sprott D, Kanczkowski W, Tzanavari T, Bdeir M, Bergmann S, Cartellieri M, Bachmann M, Nikolakopoulou P, Androutsellis-Theotokis A, Siegert G, Bornstein SR, Muders MH, Boon L, Karalis KP, Lutgens E, Chavakis T. Chatzigeorgiou A, et al. Hepatology. 2014 Oct;60(4):1196-210. doi: 10.1002/hep.27233. Epub 2014 Aug 21. Hepatology. 2014. PMID: 24845056
Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release.
Masjkur J, Arps-Forker C, Poser SW, Nikolakopoulou P, Toutouna L, Chenna R, Chavakis T, Chatzigeorgiou A, Chen LS, Dubrovska A, Choudhary P, Uphues I, Mark M, Bornstein SR, Androutsellis-Theotokis A. Masjkur J, et al. Among authors: chatzigeorgiou a. J Biol Chem. 2014 Dec 19;289(51):35503-16. doi: 10.1074/jbc.M114.590687. Epub 2014 Nov 4. J Biol Chem. 2014. PMID: 25371201 Free PMC article.
94 results