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Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations.
Le Dour C, Chatzifrangkeskou M, Macquart C, Magiera MM, Peccate C, Jouve C, Virtanen L, Heliö T, Aalto-Setälä K, Crasto S, Cadot B, Cardoso D, Mougenot N, Adesse D, Di Pasquale E, Hulot JS, Taimen P, Janke C, Muchir A. Le Dour C, et al. Among authors: chatzifrangkeskou m. Nat Commun. 2022 Dec 22;13(1):7886. doi: 10.1038/s41467-022-35639-x. Nat Commun. 2022. PMID: 36550158 Free PMC article.
53BP1-mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling.
Tsaridou S, Velimezi G, Willenbrock F, Chatzifrangkeskou M, Elsayed W, Panagopoulos A, Karamitros D, Gorgoulis V, Lygerou Z, Roukos V, O'Neill E, Pefani DE. Tsaridou S, et al. Among authors: chatzifrangkeskou m. EMBO Rep. 2022 Aug 3;23(8):e54483. doi: 10.15252/embr.202154483. Epub 2022 Jun 27. EMBO Rep. 2022. PMID: 35758159 Free PMC article.
The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies.
Vignier N, Chatzifrangkeskou M, Pinton L, Wioland H, Marais T, Lemaitre M, Le Dour C, Peccate C, Cardoso D, Schmitt A, Wu W, Biferi MG, Naouar N, Macquart C, Beuvin M, Decostre V, Bonne G, Romet-Lemonne G, Worman HJ, Tedesco FS, Jégou A, Muchir A. Vignier N, et al. Among authors: chatzifrangkeskou m. Cell Rep. 2021 Aug 24;36(8):109601. doi: 10.1016/j.celrep.2021.109601. Cell Rep. 2021. PMID: 34433058 Free PMC article.
Mutated lamin A modulates stiffness in muscle cells.
Chatzifrangkeskou M, Kah D, Lange JR, Goldmann WH, Muchir A. Chatzifrangkeskou M, et al. Biochem Biophys Res Commun. 2020 Aug 27;529(3):861-867. doi: 10.1016/j.bbrc.2020.05.102. Epub 2020 Jun 12. Biochem Biophys Res Commun. 2020. PMID: 32540097
When Hippo meets actin in the nucleus.
Chatzifrangkeskou M, O'Neill E. Chatzifrangkeskou M, et al. Mol Cell Oncol. 2019 Jul 29;6(5):e1638728. doi: 10.1080/23723556.2019.1638728. eCollection 2019. Mol Cell Oncol. 2019. PMID: 31528703 Free PMC article.
RASSF1A is required for the maintenance of nuclear actin levels.
Chatzifrangkeskou M, Pefani DE, Eyres M, Vendrell I, Fischer R, Pankova D, O'Neill E. Chatzifrangkeskou M, et al. EMBO J. 2019 Aug 15;38(16):e101168. doi: 10.15252/embj.2018101168. Epub 2019 Jun 7. EMBO J. 2019. PMID: 31414556 Free PMC article.
18 results