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Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model.
Scheiner M, Hoffmann M, He F, Poeta E, Chatonnet A, Monti B, Maurice T, Decker M. Scheiner M, et al. Among authors: chatonnet a. J Med Chem. 2021 Jul 8;64(13):9302-9320. doi: 10.1021/acs.jmedchem.1c00534. Epub 2021 Jun 21. J Med Chem. 2021. PMID: 34152756
Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Dolles D, Hoffmann M, Gunesch S, Marinelli O, Möller J, Santoni G, Chatonnet A, Lohse MJ, Wittmann HJ, Strasser A, Nabissi M, Maurice T, Decker M. Dolles D, et al. Among authors: chatonnet a. J Med Chem. 2018 Feb 22;61(4):1646-1663. doi: 10.1021/acs.jmedchem.7b01760. Epub 2018 Feb 5. J Med Chem. 2018. PMID: 29400965
Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat.
Babbitt PC, Bagos PG, Bairoch A, Bateman A, Chatonnet A, Chen MJ, Craik DJ, Finn RD, Gloriam D, Haft DH, Henrissat B, Holliday GL, Isberg V, Kaas Q, Landsman D, Lenfant N, Manning G, Nagano N, Srinivasan N, O'Donovan C, Pruitt KD, Sowdhamini R, Rawlings ND, Saier MH Jr, Sharman JL, Spedding M, Tsirigos KD, Vastermark A, Vriend G. Babbitt PC, et al. Among authors: chatonnet a. Database (Oxford). 2015 Jul 11;2015:bav063. doi: 10.1093/database/bav063. eCollection 2015. Database (Oxford). 2015. PMID: 26284514 Free PMC article.
Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.
Torrent J, Vilchez-Acosta A, Muñoz-Torrero D, Trovaslet M, Nachon F, Chatonnet A, Grznarova K, Acquatella-Tran Van Ba I, Le Goffic R, Herzog L, Béringue V, Rezaei H. Torrent J, et al. Among authors: chatonnet a. Acta Neuropathol Commun. 2015 Apr 3;3:18. doi: 10.1186/s40478-015-0188-0. Acta Neuropathol Commun. 2015. PMID: 25853328 Free PMC article.
73 results