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Lysine catabolism reprograms tumour immunity through histone crotonylation.
Nature. 2023 May;617(7962):818-826. doi: 10.1038/s41586-023-06061-0. Epub 2023 May 17.
Nature. 2023.
PMID: 37198486
Free PMC article.
Dynamic protein deacetylation is a limited carbon source for acetyl-CoA-dependent metabolism.
Soaita I, Megill E, Kantner D, Chatoff A, Cheong YJ, Clarke P, Arany Z, Snyder NW, Wellen KE, Trefely S.
Soaita I, et al. Among authors: chatoff a.
J Biol Chem. 2023 Jun;299(6):104772. doi: 10.1016/j.jbc.2023.104772. Epub 2023 May 2.
J Biol Chem. 2023.
PMID: 37142219
Free PMC article.
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De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression.
Tangudu NK, Buj R, Wang H, Wang J, Cole AR, Uboveja A, Fang R, Amalric A, Yang B, Chatoff A, Crispim CV, Sajjakulnukit P, Lyons MA, Cooper K, Hempel N, Lyssiotis CA, Chandran UR, Snyder NW, Aird KM.
Tangudu NK, et al. Among authors: chatoff a.
Cancer Res Commun. 2024 May 2;4(5):1174-1188. doi: 10.1158/2767-9764.CRC-23-0450.
Cancer Res Commun. 2024.
PMID: 38626341
Free PMC article.
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The helminth-derived peptide, FhHDM-1, reverses the trained phenotype of NOD bone-marrow-derived macrophages and regulates proinflammatory responses.
Quinteros SL, Snyder NW, Chatoff A, Ryan F, O'Brien B, Donnelly S.
Quinteros SL, et al. Among authors: chatoff a.
Eur J Immunol. 2024 Apr 5:e2350643. doi: 10.1002/eji.202350643. Online ahead of print.
Eur J Immunol. 2024.
PMID: 38581085
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KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation.
Budyagan K, Cannon AC, Chatoff A, Snyder NW, Kurimchak AM, Duncan JS, Chernoff J.
Budyagan K, et al. Among authors: chatoff a.
Res Sq [Preprint]. 2024 Feb 22:rs.3.rs-3931415. doi: 10.21203/rs.3.rs-3931415/v1.
Res Sq. 2024.
PMID: 38464238
Free PMC article.
Preprint.
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αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation.
Uboveja A, Huang Z, Buj R, Amalric A, Wang H, Tangudu NK, Cole AR, Megill E, Kantner D, Chatoff A, Ahmad H, Marcinkiewicz MM, Disharoon JA, Graff S, Dahl ES, Hempel N, Stallaert W, Sidoli S, Bitler BG, Long DT, Snyder NW, Aird KM.
Uboveja A, et al. Among authors: chatoff a.
bioRxiv [Preprint]. 2024 Feb 11:2024.02.06.578742. doi: 10.1101/2024.02.06.578742.
bioRxiv. 2024.
PMID: 38370789
Free PMC article.
Preprint.
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Developmental programming: Metabolic tissue-specific changes in endoplasmic reticulum stress, mitochondrial oxidative and telomere length status induced by prenatal testosterone excess in the female sheep.
Puttabyatappa M, Ciarelli JN, Chatoff AG, Padmanabhan V.
Puttabyatappa M, et al. Among authors: chatoff ag.
Mol Cell Endocrinol. 2021 Apr 15;526:111207. doi: 10.1016/j.mce.2021.111207. Epub 2021 Feb 17.
Mol Cell Endocrinol. 2021.
PMID: 33607270
Free PMC article.
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Developmental programming: Adipose depot-specific changes and thermogenic adipocyte distribution in the female sheep.
Puttabyatappa M, Ciarelli JN, Chatoff AG, Singer K, Padmanabhan V.
Puttabyatappa M, et al. Among authors: chatoff ag.
Mol Cell Endocrinol. 2020 Mar 1;503:110691. doi: 10.1016/j.mce.2019.110691. Epub 2019 Dec 19.
Mol Cell Endocrinol. 2020.
PMID: 31863810
Free PMC article.
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