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O-GlcNAcylation, novel post-translational modification linking myocardial metabolism and cardiomyocyte circadian clock.
Durgan DJ, Pat BM, Laczy B, Bradley JA, Tsai JY, Grenett MH, Ratcliffe WF, Brewer RA, Nagendran J, Villegas-Montoya C, Zou C, Zou L, Johnson RL Jr, Dyck JR, Bray MS, Gamble KL, Chatham JC, Young ME. Durgan DJ, et al. Among authors: chatham jc. J Biol Chem. 2011 Dec 30;286(52):44606-19. doi: 10.1074/jbc.M111.278903. Epub 2011 Nov 8. J Biol Chem. 2011. PMID: 22069332 Free PMC article.
Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart.
Young ME, Brewer RA, Peliciari-Garcia RA, Collins HE, He L, Birky TL, Peden BW, Thompson EG, Ammons BJ, Bray MS, Chatham JC, Wende AR, Yang Q, Chow CW, Martino TA, Gamble KL. Young ME, et al. Among authors: chatham jc. J Biol Rhythms. 2014 Aug;29(4):257-76. doi: 10.1177/0748730414543141. J Biol Rhythms. 2014. PMID: 25238855 Free PMC article.
Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice.
Peliciari-Garcia RA, Goel M, Aristorenas JA, Shah K, He L, Yang Q, Shalev A, Bailey SM, Prabhu SD, Chatham JC, Gamble KL, Young ME. Peliciari-Garcia RA, et al. Among authors: chatham jc. Biochim Biophys Acta. 2016 Oct;1861(10):1579-95. doi: 10.1016/j.bbalip.2015.12.012. Epub 2015 Dec 22. Biochim Biophys Acta. 2016. PMID: 26721420 Free PMC article.
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Chen J, Young ME, Chatham JC, Crossman DK, Dell'Italia LJ, Shalev A. Chen J, et al. Among authors: chatham jc. Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H64-75. doi: 10.1152/ajpheart.00151.2016. Epub 2016 May 3. Am J Physiol Heart Circ Physiol. 2016. PMID: 27199118 Free PMC article.
150 results