Charnley AK - Search Results

1

Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics.

Smith AB 3rd, Charnley AK, Mesaros EF, Kikuchi O, Wang W, Benowitz A, Chu CL, Feng JJ, Chen KH, Lin A, Cheng FC, Taylor L, Hirschmann R. Smith AB 3rd, et al. Among authors: charnley ak. Org Lett. 2005 Feb 3;7(3):399-402. doi: 10.1021/ol0476974. Org Lett. 2005. PMID: 15673249

2

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains.

Smith AB 3rd, Charnley AK, Harada H, Beiger JJ, Cantin LD, Kenesky CS, Hirschmann R, Munshi S, Olsen DB, Stahlhut MW, Schleif WA, Kuo LC. Smith AB 3rd, et al. Among authors: charnley ak. Bioorg Med Chem Lett. 2006 Feb 15;16(4):859-63. doi: 10.1016/j.bmcl.2005.11.011. Epub 2005 Nov 18. Bioorg Med Chem Lett. 2006. PMID: 16298527

3

Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 1. From nonpeptide peptidomimetics to nanotubes.

Smith AB 3rd, Wang W, Charnley AK, Carroll PJ, Kenesky CS, Hirschmann R. Smith AB 3rd, et al. Among authors: charnley ak. Org Lett. 2010 Jul 2;12(13):2990-3. doi: 10.1021/ol101007n. Org Lett. 2010. PMID: 20518540 Free PMC article.

4

Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 2. Macrocyclic hexapyrrolinones.

Smith AB 3rd, Xiong H, Charnley AK, Brenner M, Mesaros EF, Kenesky CS, Di Costanzo L, Christianson DW, Hirschmann R. Smith AB 3rd, et al. Among authors: charnley ak. Org Lett. 2010 Jul 2;12(13):2994-7. doi: 10.1021/ol101008y. Org Lett. 2010. PMID: 20518572 Free PMC article.

5

Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge".

Smith AB 3rd, Charnley AK, Hirschmann R. Smith AB 3rd, et al. Among authors: charnley ak. Acc Chem Res. 2011 Mar 15;44(3):180-93. doi: 10.1021/ar1001186. Epub 2010 Dec 22. Acc Chem Res. 2011. PMID: 21175156 Free PMC article.

6

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors.

Smith AB 3rd, Cantin LD, Pasternak A, Guise-Zawacki L, Yao W, Charnley AK, Barbosa J, Sprengeler PA, Hirschmann R, Munshi S, Olsen DB, Schleif WA, Kuo LC. Smith AB 3rd, et al. Among authors: charnley ak. J Med Chem. 2003 May 8;46(10):1831-44. doi: 10.1021/jm0204587. J Med Chem. 2003. PMID: 12723947

7

Two-dimensional infrared investigation of N-acetyl tryptophan methyl amide in solution.

Bagchi S, Kim YS, Charnley AK, Smith AB 3rd, Hochstrasser RM. Bagchi S, et al. Among authors: charnley ak. J Phys Chem B. 2007 Mar 22;111(11):3010-8. doi: 10.1021/jp067348m. Epub 2007 Feb 28. J Phys Chem B. 2007. PMID: 17388413

8

Equilibrium exchange processes of the aqueous tryptophan dipeptide.

Bagchi S, Charnley AK, Smith Iii AB, Hochstrasser RM. Bagchi S, et al. Among authors: charnley ak. J Phys Chem B. 2009 Jun 18;113(24):8412-7. doi: 10.1021/jp811168x. J Phys Chem B. 2009. PMID: 19459617 Free PMC article.

9

Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.

Haffner CD, Charnley AK, Aquino CJ, Casillas L, Convery MA, Cox JA, Elban MA, Goodwin NC, Gough PJ, Haile PA, Hughes TV, Knapp-Reed B, Kreatsoulas C, Lakdawala AS, Li H, Lian Y, Lipshutz D, Mehlmann JF, Ouellette M, Romano J, Shewchuk L, Shu A, Votta BJ, Zhou H, Bertin J, Marquis RW. Haffner CD, et al. Among authors: charnley ak. ACS Med Chem Lett. 2019 Oct 11;10(11):1518-1523. doi: 10.1021/acsmedchemlett.9b00141. eCollection 2019 Nov 14. ACS Med Chem Lett. 2019. PMID: 31749904 Free PMC article.

10

Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity.

Charnley AK, Convery MA, Lakdawala Shah A, Jones E, Hardwicke P, Bridges A, Ouellette M, Totoritis R, Schwartz B, King BW, Wisnoski DD, Kang J, Eidam PM, Votta BJ, Gough PJ, Marquis RW, Bertin J, Casillas L. Charnley AK, et al. Bioorg Med Chem. 2015 Nov 1;23(21):7000-6. doi: 10.1016/j.bmc.2015.09.038. Epub 2015 Sep 25. Bioorg Med Chem. 2015. PMID: 26455654

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