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High-content CRISPR screening.
Bock C, Datlinger P, Chardon F, Coelho MA, Dong MB, Lawson KA, Lu T, Maroc L, Norman TM, Song B, Stanley G, Chen S, Garnett M, Li W, Moffat J, Qi LS, Shapiro RS, Shendure J, Weissman JS, Zhuang X. Bock C, et al. Among authors: chardon f. Nat Rev Methods Primers. 2022;2(1):9. doi: 10.1038/s43586-022-00098-7. Epub 2022 Feb 10. Nat Rev Methods Primers. 2022. PMID: 37214176 Free PMC article.
Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma.
Alexander J, LaPlant QC, Pattwell SS, Szulzewsky F, Cimino PJ, Caruso FP, Pugliese P, Chen Z, Chardon F, Hill AJ, Spurrell C, Ahrendsen D, Pietras A, Starita LM, Hambardzumyan D, Iavarone A, Shendure J, Holland EC. Alexander J, et al. Among authors: chardon f. Glia. 2020 Dec;68(12):2486-2502. doi: 10.1002/glia.23866. Epub 2020 Jul 4. Glia. 2020. PMID: 32621641 Free PMC article.
Precise genomic deletions using paired prime editing.
Choi J, Chen W, Suiter CC, Lee C, Chardon FM, Yang W, Leith A, Daza RM, Martin B, Shendure J. Choi J, et al. Nat Biotechnol. 2022 Feb;40(2):218-226. doi: 10.1038/s41587-021-01025-z. Epub 2021 Oct 14. Nat Biotechnol. 2022. PMID: 34650269 Free PMC article.
Chromatin context-dependent regulation and epigenetic manipulation of prime editing.
Li X, Chen W, Martin BK, Calderon D, Lee C, Choi J, Chardon FM, McDiarmid TA, Daza RM, Kim H, Lalanne JB, Nathans JF, Lee DS, Shendure J. Li X, et al. Among authors: chardon fm. Cell. 2024 May 9;187(10):2411-2427.e25. doi: 10.1016/j.cell.2024.03.020. Epub 2024 Apr 11. Cell. 2024. PMID: 38608704 Free article.
Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements.
Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin B, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J. Chardon FM, et al. bioRxiv [Preprint]. 2024 Apr 30:2023.03.28.534017. doi: 10.1101/2023.03.28.534017. bioRxiv. 2024. PMID: 37034704 Free PMC article. Preprint.
Chromatin context-dependent regulation and epigenetic manipulation of prime editing.
Li X, Chen W, Martin BK, Calderon D, Lee C, Choi J, Chardon FM, McDiarmid T, Kim H, Lalanne JB, Nathans JF, Shendure J. Li X, et al. Among authors: chardon fm. bioRxiv [Preprint]. 2023 Apr 12:2023.04.12.536587. doi: 10.1101/2023.04.12.536587. bioRxiv. 2023. PMID: 37090511 Free PMC article. Updated. Preprint.
MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis.
Serres MP, Shaughnessy R, Escot S, Hammich H, Cuvelier F, Salles A, Rocancourt M, Verdon Q, Gaffuri AL, Sourigues Y, Malherbe G, Velikovsky L, Chardon F, Sassoon N, Tinevez JY, Callebaut I, Formstecher E, Houdusse A, David NB, Pylypenko O, Echard A. Serres MP, et al. Among authors: chardon f. Dev Cell. 2023 Nov 20;58(22):2477-2494.e8. doi: 10.1016/j.devcel.2023.09.010. Epub 2023 Oct 23. Dev Cell. 2023. PMID: 37875118
74 results