Chapple JP - Search Results

1

Polycystin-2 Is Required for Chondrocyte Mechanotransduction and Traffics to the Primary Cilium in Response to Mechanical Stimulation.

Thompson CL, McFie M, Chapple JP, Beales P, Knight MM. Thompson CL, et al. Among authors: chapple jp. Int J Mol Sci. 2021 Apr 21;22(9):4313. doi: 10.3390/ijms22094313. Int J Mol Sci. 2021. PMID: 33919210 Free PMC article.

2

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.

Ross AJ, May-Simera H, Eichers ER, Kai M, Hill J, Jagger DJ, Leitch CC, Chapple JP, Munro PM, Fisher S, Tan PL, Phillips HM, Leroux MR, Henderson DJ, Murdoch JN, Copp AJ, Eliot MM, Lupski JR, Kemp DT, Dollfus H, Tada M, Katsanis N, Forge A, Beales PL. Ross AJ, et al. Among authors: chapple jp. Nat Genet. 2005 Oct;37(10):1135-40. doi: 10.1038/ng1644. Epub 2005 Sep 18. Nat Genet. 2005. PMID: 16170314

3

Heat shock induces rapid resorption of primary cilia.

Prodromou NV, Thompson CL, Osborn DP, Cogger KF, Ashworth R, Knight MM, Beales PL, Chapple JP. Prodromou NV, et al. Among authors: chapple jp. J Cell Sci. 2012 Sep 15;125(Pt 18):4297-305. doi: 10.1242/jcs.100545. Epub 2012 Jun 20. J Cell Sci. 2012. PMID: 22718348 Free PMC article.

4

Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium.

Wann AK, Thompson CL, Chapple JP, Knight MM. Wann AK, et al. Among authors: chapple jp. Cilia. 2013 Dec 13;2(1):17. doi: 10.1186/2046-2530-2-17. Cilia. 2013. PMID: 24330727 Free PMC article.

5

Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes.

Thompson CL, Chapple JP, Knight MM. Thompson CL, et al. Among authors: chapple jp. Osteoarthritis Cartilage. 2014 Mar;22(3):490-8. doi: 10.1016/j.joca.2013.12.016. Epub 2014 Jan 21. Osteoarthritis Cartilage. 2014. PMID: 24457103 Free PMC article.

6

The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity.

Wann AK, Chapple JP, Knight MM. Wann AK, et al. Among authors: chapple jp. Cell Signal. 2014 Aug;26(8):1735-42. doi: 10.1016/j.cellsig.2014.04.004. Epub 2014 Apr 12. Cell Signal. 2014. PMID: 24726893 Free PMC article.

7

Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation.

Dalbay MT, Thorpe SD, Connelly JT, Chapple JP, Knight MM. Dalbay MT, et al. Among authors: chapple jp. Stem Cells. 2015 Jun;33(6):1952-61. doi: 10.1002/stem.1975. Stem Cells. 2015. PMID: 25693948 Free PMC article.

8

Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β.

Thompson CL, Patel R, Kelly TA, Wann AK, Hung CT, Chapple JP, Knight MM. Thompson CL, et al. Among authors: chapple jp. Arthritis Res Ther. 2015 Dec 24;17:373. doi: 10.1186/s13075-015-0891-z. Arthritis Res Ther. 2015. PMID: 26705100 Free PMC article.

9

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.

Schwarz N, Lane A, Jovanovic K, Parfitt DA, Aguila M, Thompson CL, da Cruz L, Coffey PJ, Chapple JP, Hardcastle AJ, Cheetham ME. Schwarz N, et al. Among authors: chapple jp. Hum Mol Genet. 2017 Jul 1;26(13):2480-2492. doi: 10.1093/hmg/ddx143. Hum Mol Genet. 2017. PMID: 28444310 Free PMC article.

10

Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis.

Zhang J, Dalbay MT, Luo X, Vrij E, Barbieri D, Moroni L, de Bruijn JD, van Blitterswijk CA, Chapple JP, Knight MM, Yuan H. Zhang J, et al. Among authors: chapple jp. Acta Biomater. 2017 Jul 15;57:487-497. doi: 10.1016/j.actbio.2017.04.004. Epub 2017 Apr 27. Acta Biomater. 2017. PMID: 28456657 Free PMC article.

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