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Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Romano LEL, Aw WY, Hixson KM, Novoselova TV, Havener TM, Howell S, Taylor-Blake B, Hall CL, Xing L, Beri J, Nethisinghe S, Perna L, Hatimy A, Altadonna GC, Graves LM, Herring LE, Hickey AJ, Thalassinos K, Chapple JP, Wolter JM. Romano LEL, et al. Among authors: chapple jp. Cell Rep. 2022 Nov 1;41(5):111580. doi: 10.1016/j.celrep.2022.111580. Cell Rep. 2022. PMID: 36323248 Free PMC article.
J-domain proteins: From molecular mechanisms to diseases.
Marszalek J, De Los Rios P, Cyr D, Mayer MP, Adupa V, Andréasson C, Blatch GL, Braun JEA, Brodsky JL, Bukau B, Chapple JP, Conz C, Dementin S, Genevaux P, Genest O, Goloubinoff P, Gestwicki J, Hammond CM, Hines JK, Ishikawa K, Joachimiak LA, Kirstein J, Liberek K, Mokranjac D, Nillegoda N, Ramos CHI, Rebeaud M, Ron D, Rospert S, Sahi C, Shalgi R, Tomiczek B, Ushioda R, Ustyantseva E, Ye Y, Zylicz M, Kampinga HH. Marszalek J, et al. Among authors: chapple jp. Cell Stress Chaperones. 2024 Feb;29(1):21-33. doi: 10.1016/j.cstres.2023.12.002. Epub 2023 Dec 23. Cell Stress Chaperones. 2024. PMID: 38320449 Free PMC article.
HSP70-HSP90 Chaperone Networking in Protein-Misfolding Disease.
Prodromou C, Aran-Guiu X, Oberoi J, Perna L, Chapple JP, van der Spuy J. Prodromou C, et al. Among authors: chapple jp. Subcell Biochem. 2023;101:389-425. doi: 10.1007/978-3-031-14740-1_13. Subcell Biochem. 2023. PMID: 36520314 Review.
Antiproliferative effects of metformin in cellular models of pheochromocytoma.
Meireles CG, Lourenço de Lima C, Martins de Paula Oliveira M, Abe da Rocha Miranda R, Romano L, Yo-Stella Brashaw T, Neves da Silva Guerra E, de Assis Rocha Neves F, Chapple JP, Simeoni LA, Lofrano-Porto A. Meireles CG, et al. Among authors: chapple jp. Mol Cell Endocrinol. 2022 Jan 1;539:111484. doi: 10.1016/j.mce.2021.111484. Epub 2021 Oct 9. Mol Cell Endocrinol. 2022. PMID: 34637881
77 results