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Convergent somatic mutations in metabolism genes in chronic liver disease.
Ng SWK, Rouhani FJ, Brunner SF, Brzozowska N, Aitken SJ, Yang M, Abascal F, Moore L, Nikitopoulou E, Chappell L, Leongamornlert D, Ivovic A, Robinson P, Butler T, Sanders MA, Williams N, Coorens THH, Teague J, Raine K, Butler AP, Hooks Y, Wilson B, Birtchnell N, Naylor H, Davies SE, Stratton MR, Martincorena I, Rahbari R, Frezza C, Hoare M, Campbell PJ. Ng SWK, et al. Among authors: chappell l. Nature. 2021 Oct;598(7881):473-478. doi: 10.1038/s41586-021-03974-6. Epub 2021 Oct 13. Nature. 2021. PMID: 34646017
Clonal diversification and histogenesis of malignant germ cell tumours.
Oliver TRW, Chappell L, Sanghvi R, Deighton L, Ansari-Pour N, Dentro SC, Young MD, Coorens THH, Jung H, Butler T, Neville MDC, Leongamornlert D, Sanders MA, Hooks Y, Cagan A, Mitchell TJ, Cortes-Ciriano I, Warren AY, Wedge DC, Heer R, Coleman N, Murray MJ, Campbell PJ, Rahbari R, Behjati S. Oliver TRW, et al. Among authors: chappell l. Nat Commun. 2022 Aug 11;13(1):4272. doi: 10.1038/s41467-022-31375-4. Nat Commun. 2022. PMID: 35953478 Free PMC article.
Found in translation.
Chappell L. Chappell L. Nat Rev Microbiol. 2014 Apr;12(4):238. doi: 10.1038/nrmicro3243. Epub 2014 Mar 10. Nat Rev Microbiol. 2014. PMID: 24608332 No abstract available.
Vector transmission regulates immune control of Plasmodium virulence.
Spence PJ, Jarra W, Lévy P, Reid AJ, Chappell L, Brugat T, Sanders M, Berriman M, Langhorne J. Spence PJ, et al. Among authors: chappell l. Nature. 2013 Jun 13;498(7453):228-31. doi: 10.1038/nature12231. Epub 2013 May 29. Nature. 2013. PMID: 23719378 Free PMC article.
Single-Cell (Multi)omics Technologies.
Chappell L, Russell AJC, Voet T. Chappell L, et al. Annu Rev Genomics Hum Genet. 2018 Aug 31;19:15-41. doi: 10.1146/annurev-genom-091416-035324. Epub 2018 May 4. Annu Rev Genomics Hum Genet. 2018. PMID: 29727584 Review.
The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites.
Charnaud SC, Dixon MWA, Nie CQ, Chappell L, Sanders PR, Nebl T, Hanssen E, Berriman M, Chan JA, Blanch AJ, Beeson JG, Rayner JC, Przyborski JM, Tilley L, Crabb BS, Gilson PR. Charnaud SC, et al. Among authors: chappell l. PLoS One. 2017 Jul 21;12(7):e0181656. doi: 10.1371/journal.pone.0181656. eCollection 2017. PLoS One. 2017. PMID: 28732045 Free PMC article.
Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites.
Brochet M, Collins MO, Smith TK, Thompson E, Sebastian S, Volkmann K, Schwach F, Chappell L, Gomes AR, Berriman M, Rayner JC, Baker DA, Choudhary J, Billker O. Brochet M, et al. Among authors: chappell l. PLoS Biol. 2014 Mar 4;12(3):e1001806. doi: 10.1371/journal.pbio.1001806. eCollection 2014 Mar. PLoS Biol. 2014. PMID: 24594931 Free PMC article.
442 results