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Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification.
Meistermann D, Bruneau A, Loubersac S, Reignier A, Firmin J, François-Campion V, Kilens S, Lelièvre Y, Lammers J, Feyeux M, Hulin P, Nedellec S, Bretin B, Castel G, Allègre N, Covin S, Bihouée A, Soumillon M, Mikkelsen T, Barrière P, Chazaud C, Chappell J, Pasque V, Bourdon J, Fréour T, David L. Meistermann D, et al. Among authors: chappell j. Cell Stem Cell. 2021 Sep 2;28(9):1625-1640.e6. doi: 10.1016/j.stem.2021.04.027. Epub 2021 May 17. Cell Stem Cell. 2021. PMID: 34004179 Free article.
Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming.
Janiszewski A, Talon I, Chappell J, Collombet S, Song J, De Geest N, To SK, Bervoets G, Marin-Bejar O, Provenzano C, Vanheer L, Marine JC, Rambow F, Pasque V. Janiszewski A, et al. Among authors: chappell j. Genome Res. 2019 Oct;29(10):1659-1672. doi: 10.1101/gr.249706.119. Epub 2019 Sep 12. Genome Res. 2019. PMID: 31515287 Free PMC article.
Tox4 modulates cell fate reprogramming.
Vanheer L, Song J, De Geest N, Janiszewski A, Talon I, Provenzano C, Oh T, Chappell J, Pasque V. Vanheer L, et al. Among authors: chappell j. J Cell Sci. 2019 Oct 22;132(20):jcs232223. doi: 10.1242/jcs.232223. J Cell Sci. 2019. PMID: 31519808 Free PMC article.
Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.
Vennekens A, Laporte E, Hermans F, Cox B, Modave E, Janiszewski A, Nys C, Kobayashi H, Malengier-Devlies B, Chappell J, Matthys P, Garcia MI, Pasque V, Lambrechts D, Vankelecom H. Vennekens A, et al. Among authors: chappell j. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2100052118. doi: 10.1073/pnas.2100052118. Proc Natl Acad Sci U S A. 2021. PMID: 34161279 Free PMC article.
Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction.
Zijlmans DW, Talon I, Verhelst S, Bendall A, Van Nerum K, Javali A, Malcolm AA, van Knippenberg SSFA, Biggins L, To SK, Janiszewski A, Admiraal D, Knops R, Corthout N, Balaton BP, Georgolopoulos G, Panda A, Bhanu NV, Collier AJ, Fabian C, Allsop RN, Chappell J, Pham TXA, Oberhuemer M, Ertekin C, Vanheer L, Athanasouli P, Lluis F, Deforce D, Jansen JH, Garcia BA, Vermeulen M, Rivron N, Dhaenens M, Marks H, Rugg-Gunn PJ, Pasque V. Zijlmans DW, et al. Among authors: chappell j. Nat Cell Biol. 2022 Jun;24(6):858-871. doi: 10.1038/s41556-022-00932-w. Epub 2022 Jun 13. Nat Cell Biol. 2022. PMID: 35697783 Free PMC article.
Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells.
Pham TXA, Panda A, Kagawa H, To SK, Ertekin C, Georgolopoulos G, van Knippenberg SSFA, Allsop RN, Bruneau A, Chui JS, Vanheer L, Janiszewski A, Chappell J, Oberhuemer M, Tchinda RS, Talon I, Khodeer S, Rossant J, Lluis F, David L, Rivron N, Balaton BP, Pasque V. Pham TXA, et al. Among authors: chappell j. Cell Stem Cell. 2022 Sep 1;29(9):1346-1365.e10. doi: 10.1016/j.stem.2022.08.001. Cell Stem Cell. 2022. PMID: 36055191 Free PMC article.
Inferring regulators of cell identity in the human adult pancreas.
Vanheer L, Fantuzzi F, To SK, Schiavo A, Van Haele M, Ostyn T, Haesen T, Yi X, Janiszewski A, Chappell J, Rihoux A, Sawatani T, Roskams T, Pattou F, Kerr-Conte J, Cnop M, Pasque V. Vanheer L, et al. Among authors: chappell j. NAR Genom Bioinform. 2023 Jul 10;5(3):lqad068. doi: 10.1093/nargab/lqad068. eCollection 2023 Sep. NAR Genom Bioinform. 2023. PMID: 37435358 Free PMC article.
Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling.
Harman JL, Dobnikar L, Chappell J, Stokell BG, Dalby A, Foote K, Finigan A, Freire-Pritchett P, Taylor AL, Worssam MD, Madsen RR, Loche E, Uryga A, Bennett MR, Jørgensen HF. Harman JL, et al. Among authors: chappell j. Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2289-2302. doi: 10.1161/ATVBAHA.119.312765. Epub 2019 Aug 22. Arterioscler Thromb Vasc Biol. 2019. PMID: 31434493 Free PMC article.
709 results