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Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS.
Eitan C, Siany A, Barkan E, Olender T, van Eijk KR, Moisse M, Farhan SMK, Danino YM, Yanowski E, Marmor-Kollet H, Rivkin N, Yacovzada NS, Hung ST, Cooper-Knock J, Yu CH, Louis C, Masters SL, Kenna KP, van der Spek RAA, Sproviero W, Al Khleifat A, Iacoangeli A, Shatunov A, Jones AR, Elbaz-Alon Y, Cohen Y, Chapnik E, Rothschild D, Weissbrod O, Beck G, Ainbinder E, Ben-Dor S, Werneburg S, Schafer DP, Brown RH Jr, Shaw PJ, Van Damme P, van den Berg LH, Phatnani H, Segal E, Ichida JK, Al-Chalabi A, Veldink JH; Project MinE ALS Sequencing Consortium; NYGC ALS Consortium; Hornstein E. Eitan C, et al. Among authors: chapnik e. Nat Neurosci. 2022 Apr;25(4):433-445. doi: 10.1038/s41593-022-01040-6. Epub 2022 Mar 31. Nat Neurosci. 2022. PMID: 35361972 Free PMC article.
Efficiency and specificity in microRNA biogenesis.
Barad O, Mann M, Chapnik E, Shenoy A, Blelloch R, Barkai N, Hornstein E. Barad O, et al. Among authors: chapnik e. Nat Struct Mol Biol. 2012 May 13;19(6):650-2. doi: 10.1038/nsmb.2293. Nat Struct Mol Biol. 2012. PMID: 22580560 Free PMC article.
Rac1 functions downstream of miR-142 in regulation of erythropoiesis.
Rivkin N, Chapnik E, Birger Y, Yanowski E, Curato C, Mildner A, Porat Z, Amir G, Izraeli S, Jung S, Hornstein E. Rivkin N, et al. Among authors: chapnik e. Haematologica. 2017 Dec;102(12):e476-e480. doi: 10.3324/haematol.2017.171736. Epub 2017 Sep 14. Haematologica. 2017. PMID: 28912177 Free PMC article. No abstract available.
MicroRNA-142 controls thymocyte proliferation.
Mildner A, Chapnik E, Varol D, Aychek T, Lampl N, Rivkin N, Bringmann A, Paul F, Boura-Halfon S, Hayoun YS, Barnett-Itzhaki Z, Amit I, Hornstein E, Jung S. Mildner A, et al. Among authors: chapnik e. Eur J Immunol. 2017 Jul;47(7):1142-1152. doi: 10.1002/eji.201746987. Epub 2017 Jun 6. Eur J Immunol. 2017. PMID: 28471480 Free article.
Erythrocyte survival is controlled by microRNA-142.
Rivkin N, Chapnik E, Mildner A, Barshtein G, Porat Z, Kartvelishvily E, Dadosh T, Birger Y, Amir G, Yedgar S, Izraeli S, Jung S, Hornstein E. Rivkin N, et al. Among authors: chapnik e. Haematologica. 2017 Apr;102(4):676-685. doi: 10.3324/haematol.2016.156109. Epub 2016 Dec 1. Haematologica. 2017. PMID: 27909218 Free PMC article.
miRNA malfunction causes spinal motor neuron disease.
Haramati S, Chapnik E, Sztainberg Y, Eilam R, Zwang R, Gershoni N, McGlinn E, Heiser PW, Wills AM, Wirguin I, Rubin LL, Misawa H, Tabin CJ, Brown R Jr, Chen A, Hornstein E. Haramati S, et al. Among authors: chapnik e. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13111-6. doi: 10.1073/pnas.1006151107. Epub 2010 Jun 29. Proc Natl Acad Sci U S A. 2010. PMID: 20616011 Free PMC article.
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