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Regenerative activity of the lung after epithelial injury.
Vaughan AE, Chapman HA. Vaughan AE, et al. Among authors: chapman ha. Biochim Biophys Acta. 2013 Jul;1832(7):922-30. doi: 10.1016/j.bbadis.2012.11.020. Epub 2012 Dec 5. Biochim Biophys Acta. 2013. PMID: 23219956 Free article. Review.
Local lung hypoxia determines epithelial fate decisions during alveolar regeneration.
Xi Y, Kim T, Brumwell AN, Driver IH, Wei Y, Tan V, Jackson JR, Xu J, Lee DK, Gotts JE, Matthay MA, Shannon JM, Chapman HA, Vaughan AE. Xi Y, et al. Among authors: chapman ha. Nat Cell Biol. 2017 Aug;19(8):904-914. doi: 10.1038/ncb3580. Epub 2017 Jul 24. Nat Cell Biol. 2017. PMID: 28737769 Free PMC article.
Persistent Pathology in Influenza-Infected Mouse Lungs.
Kanegai CM, Xi Y, Donne ML, Gotts JE, Driver IH, Amidzic G, Lechner AJ, Jones KD, Vaughan AE, Chapman HA, Rock JR. Kanegai CM, et al. Among authors: chapman ha. Am J Respir Cell Mol Biol. 2016 Oct;55(4):613-615. doi: 10.1165/rcmb.2015-0387LE. Am J Respir Cell Mol Biol. 2016. PMID: 27689795 Free PMC article. No abstract available.
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells.
Kathiriya JJ, Wang C, Zhou M, Brumwell A, Cassandras M, Le Saux CJ, Cohen M, Alysandratos KD, Wang B, Wolters P, Matthay M, Kotton DN, Chapman HA, Peng T. Kathiriya JJ, et al. Among authors: chapman ha. Nat Cell Biol. 2022 Jan;24(1):10-23. doi: 10.1038/s41556-021-00809-4. Epub 2021 Dec 30. Nat Cell Biol. 2022. PMID: 34969962 Free PMC article.
Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Basil MC, et al. Among authors: chapman ha. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30. Nature. 2022. PMID: 35355013 Free PMC article.
206 results