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Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes.
Gaffney DO, Jennings EQ, Anderson CC, Marentette JO, Shi T, Schou Oxvig AM, Streeter MD, Johannsen M, Spiegel DA, Chapman E, Roede JR, Galligan JJ. Gaffney DO, et al. Among authors: chapman e. Cell Chem Biol. 2020 Feb 20;27(2):206-213.e6. doi: 10.1016/j.chembiol.2019.11.005. Epub 2019 Nov 22. Cell Chem Biol. 2020. PMID: 31767537 Free PMC article.
Selective inhibition of p97 by chlorinated analogues of dehydrocurvularin.
Tillotson J, Bashyal BP, Kang M, Shi T, De La Cruz F, Gunatilaka AA, Chapman E. Tillotson J, et al. Among authors: chapman e. Org Biomol Chem. 2016 Jul 7;14(25):5918-21. doi: 10.1039/c6ob00560h. Epub 2016 May 25. Org Biomol Chem. 2016. PMID: 27223265 Free PMC article.
An epigenetic modifier induces production of (10'S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla.
Gubiani JR, Wijeratne EM, Shi T, Araujo AR, Arnold AE, Chapman E, Gunatilaka AA. Gubiani JR, et al. Among authors: chapman e. Bioorg Med Chem. 2017 Mar 15;25(6):1860-1866. doi: 10.1016/j.bmc.2017.01.048. Epub 2017 Feb 3. Bioorg Med Chem. 2017. PMID: 28202316 Free PMC article.
Sirtuin 2 Regulates Protein LactoylLys Modifications.
Jennings EQ, Ray JD, Zerio CJ, Trujillo MN, McDonald DM, Chapman E, Spiegel DA, Galligan JJ. Jennings EQ, et al. Among authors: chapman e. Chembiochem. 2021 Jun 15;22(12):2102-2106. doi: 10.1002/cbic.202000883. Epub 2021 Apr 9. Chembiochem. 2021. PMID: 33725370 Free PMC article.
CHML is an NRF2 target gene that regulates mTOR function.
Dodson M, Dai W, Anandhan A, Schmidlin CJ, Liu P, Wilson NC, Wei Y, Kitamura N, Galligan JJ, Ooi A, Chapman E, Zhang DD. Dodson M, et al. Among authors: chapman e. Mol Oncol. 2022 Apr;16(8):1714-1727. doi: 10.1002/1878-0261.13194. Epub 2022 Feb 28. Mol Oncol. 2022. PMID: 35184380 Free PMC article.
Lactoylglutathione promotes inflammatory signaling in macrophages.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: chapman e. bioRxiv [Preprint]. 2023 Oct 10:2023.10.10.561739. doi: 10.1101/2023.10.10.561739. bioRxiv. 2023. PMID: 37873172 Free PMC article. Updated. Preprint.
837 results