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TRPML Cation Channels in Inflammation and Immunity.
Spix B, Chao YK, Abrahamian C, Chen CC, Grimm C. Spix B, et al. Among authors: chao yk. Front Immunol. 2020 Feb 28;11:225. doi: 10.3389/fimmu.2020.00225. eCollection 2020. Front Immunol. 2020. PMID: 32184778 Free PMC article. Review.
Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2.
Netcharoensirisuk P, Abrahamian C, Tang R, Chen CC, Rosato AS, Beyers W, Chao YK, Filippini A, Di Pietro S, Bartel K, Biel M, Vollmar AM, Umehara K, De-Eknamkul W, Grimm C. Netcharoensirisuk P, et al. Among authors: chao yk. Sci Rep. 2021 Apr 19;11(1):8515. doi: 10.1038/s41598-021-88196-6. Sci Rep. 2021. PMID: 33875769 Free PMC article.
Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells.
Siow WX, Kabiri Y, Tang R, Chao YK, Plesch E, Eberhagen C, Flenkenthaler F, Fröhlich T, Bracher F, Grimm C, Biel M, Zischka H, Vollmar AM, Bartel K. Siow WX, et al. Among authors: chao yk. J Cell Sci. 2022 Mar 15;135(6):jcs259455. doi: 10.1242/jcs.259455. Epub 2022 Mar 21. J Cell Sci. 2022. PMID: 35274126 Free PMC article.
Small Molecules for Early Endosome-Specific Patch Clamping.
Chen CC, Butz ES, Chao YK, Grishchuk Y, Becker L, Heller S, Slaugenhaupt SA, Biel M, Wahl-Schott C, Grimm C. Chen CC, et al. Among authors: chao yk. Cell Chem Biol. 2017 Jul 20;24(7):907-916.e4. doi: 10.1016/j.chembiol.2017.05.025. Cell Chem Biol. 2017. PMID: 28732201 Free article.
TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms.
Chao YK, Schludi V, Chen CC, Butz E, Nguyen ONP, Müller M, Krüger J, Kammerbauer C, Ben-Johny M, Vollmar AM, Berking C, Biel M, Wahl-Schott CA, Grimm C. Chao YK, et al. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8595-E8602. doi: 10.1073/pnas.1705739114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923947 Free PMC article.
207 results