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Baicalein significantly protects human retinal pigment epithelium cells against H₂O₂-induced oxidative stress by scavenging reactive oxygen species and downregulating the expression of matrix metalloproteinase-9 and vascular endothelial growth factor.
Liu JH, Wann H, Chen MM, Pan WH, Chen YC, Liu CM, Yeh MY, Tsai SK, Young MS, Chuang HY, Chao FP, Chao HM. Liu JH, et al. Among authors: chao hm, chao fp. J Ocul Pharmacol Ther. 2010 Oct;26(5):421-9. doi: 10.1089/jop.2010.0063. J Ocul Pharmacol Ther. 2010. PMID: 20879805
Baicalein protects against retinal ischemia by antioxidation, antiapoptosis, downregulation of HIF-1α, VEGF, and MMP-9 and upregulation of HO-1.
Chao HM, Chuang MJ, Liu JH, Liu XQ, Ho LK, Pan WH, Zhang XM, Liu CM, Tsai SK, Kong CW, Lee SD, Chen MM, Chao FP. Chao HM, et al. Among authors: chao fp. J Ocul Pharmacol Ther. 2013 Jul-Aug;29(6):539-49. doi: 10.1089/jop.2012.0179. Epub 2013 Mar 28. J Ocul Pharmacol Ther. 2013. PMID: 23537149 Free PMC article.
74 results