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Enhanced mucosal immune responses and reduced viral load in the respiratory tract of ferrets to intranasal lipid nanoparticle-based SARS-CoV-2 proteins and mRNA vaccines.
Boley PA, Lee CM, Schrock J, Yadav KK, Patil V, Suresh R, Lu S, Feng MM, Hanson J, Channappanavar R, Kenney SP, Renukaradhya GJ. Boley PA, et al. Among authors: channappanavar r. J Nanobiotechnology. 2023 Feb 22;21(1):60. doi: 10.1186/s12951-023-01816-3. J Nanobiotechnology. 2023. PMID: 36814238 Free PMC article.
Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection.
Kerr CM, Pfannenstiel JJ, Alhammad YM, Roy A, O'Connor JJ, Ghimire R, Khattabi R, Shrestha R, McDonald PR, Gao P, Johnson DK, More S, Channappanavar R, Fehr AR. Kerr CM, et al. Among authors: channappanavar r. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.574082. doi: 10.1101/2024.01.03.574082. bioRxiv. 2024. PMID: 38260573 Free PMC article. Preprint.
SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice.
Alhammad YM, Parthasarathy S, Ghimire R, Kerr CM, O'Connor JJ, Pfannenstiel JJ, Chanda D, Miller CA, Baumlin N, Salathe M, Unckless RL, Zuñiga S, Enjuanes L, More S, Channappanavar R, Fehr AR. Alhammad YM, et al. Among authors: channappanavar r. Proc Natl Acad Sci U S A. 2023 Aug 29;120(35):e2302083120. doi: 10.1073/pnas.2302083120. Epub 2023 Aug 22. Proc Natl Acad Sci U S A. 2023. PMID: 37607224 Free PMC article.
SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice.
Alhammad YM, Parthasarathy S, Ghimire R, O'Connor JJ, Kerr CM, Pfannenstiel JJ, Chanda D, Miller CA, Unckless RL, Zuniga S, Enjuanes L, More S, Channappanavar R, Fehr AR. Alhammad YM, et al. Among authors: channappanavar r. bioRxiv [Preprint]. 2023 Apr 6:2023.04.06.535927. doi: 10.1101/2023.04.06.535927. bioRxiv. 2023. PMID: 37066301 Free PMC article. Updated. Preprint.
48 results