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Discovery of M Protease Inhibitors Encoded by SARS-CoV-2.
Hung HC, Ke YY, Huang SY, Huang PN, Kung YA, Chang TY, Yen KJ, Peng TT, Chang SE, Huang CT, Tsai YR, Wu SH, Lee SJ, Lin JH, Liu BS, Sung WC, Shih SR, Chen CT, Hsu JT. Hung HC, et al. Among authors: chang se, chang ty. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00872-20. doi: 10.1128/AAC.00872-20. Print 2020 Aug 20. Antimicrob Agents Chemother. 2020. PMID: 32669265 Free PMC article.
Antiviral Activity of a Llama-Derived Single-Domain Antibody against Enterovirus A71.
Huang PN, Wang HC, Hung HC, Tseng SN, Chang TY, Chou MY, Chen YJ, Wang YM, Shih SR, Hsu JT. Huang PN, et al. Among authors: chang ty. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e01922-19. doi: 10.1128/AAC.01922-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32152074 Free PMC article.
Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor.
Yang S, Chen SJ, Hsu MF, Wu JD, Tseng CT, Liu YF, Chen HC, Kuo CW, Wu CS, Chang LW, Chen WC, Liao SY, Chang TY, Hung HH, Shr HL, Liu CY, Huang YA, Chang LY, Hsu JC, Peters CJ, Wang AH, Hsu MC. Yang S, et al. Among authors: chang ly, chang lw, chang ty. J Med Chem. 2006 Aug 10;49(16):4971-80. doi: 10.1021/jm0603926. J Med Chem. 2006. PMID: 16884309
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.
Wu CH, Coumar MS, Chu CY, Lin WH, Chen YR, Chen CT, Shiao HY, Rafi S, Wang SY, Hsu H, Chen CH, Chang CY, Chang TY, Lien TW, Fang MY, Yeh KC, Chen CP, Yeh TK, Hsieh SH, Hsu JT, Liao CC, Chao YS, Hsieh HP. Wu CH, et al. Among authors: chang cy, chang ty. J Med Chem. 2010 Oct 28;53(20):7316-26. doi: 10.1021/jm100607r. J Med Chem. 2010. PMID: 20961149
1,017 results