Chang M - Search Results

1

Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.

Bouley R, Kumarasiri M, Peng Z, Otero LH, Song W, Suckow MA, Schroeder VA, Wolter WR, Lastochkin E, Antunes NT, Pi H, Vakulenko S, Hermoso JA, Chang M, Mobashery S. Bouley R, et al. Among authors: chang m. J Am Chem Soc. 2015 Feb 11;137(5):1738-41. doi: 10.1021/jacs.5b00056. Epub 2015 Feb 2. J Am Chem Soc. 2015. PMID: 25629446 Free PMC article.

2

Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A.

Ikejiri M, Bernardo MM, Meroueh SO, Brown S, Chang M, Fridman R, Mobashery S. Ikejiri M, et al. Among authors: chang m. J Org Chem. 2005 Jul 8;70(14):5709-12. doi: 10.1021/jo050339+. J Org Chem. 2005. PMID: 15989356

3

Metabolism of a highly selective gelatinase inhibitor generates active metabolite.

Lee M, Villegas-Estrada A, Celenza G, Boggess B, Toth M, Kreitinger G, Forbes C, Fridman R, Mobashery S, Chang M. Lee M, et al. Among authors: chang m. Chem Biol Drug Des. 2007 Nov;70(5):371-82. doi: 10.1111/j.1747-0285.2007.00577.x. Epub 2007 Oct 10. Chem Biol Drug Des. 2007. PMID: 17927722

4

Conformational analyses of thiirane-based gelatinase inhibitors.

Lee M, Hesek D, Shi Q, Noll BC, Fisher JF, Chang M, Mobashery S. Lee M, et al. Among authors: chang m. Bioorg Med Chem Lett. 2008 May 15;18(10):3064-7. doi: 10.1016/j.bmcl.2007.11.131. Epub 2007 Dec 5. Bioorg Med Chem Lett. 2008. PMID: 18083555 Free PMC article.

5

Metabolism of (4-phenoxyphenylsulfonyl) methylthiirane, a selective gelatinase inhibitor.

Celenza G, Villegas-Estrada A, Lee M, Boggess B, Forbes C, Wolter WR, Suckow MA, Mobashery S, Chang M. Celenza G, et al. Among authors: chang m. Chem Biol Drug Des. 2008 Mar;71(3):187-96. doi: 10.1111/j.1747-0285.2008.00632.x. Chem Biol Drug Des. 2008. PMID: 18221479

6

A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition.

Lee M, Celenza G, Boggess B, Blase J, Shi Q, Toth M, Bernardo MM, Wolter WR, Suckow MA, Hesek D, Noll BC, Fridman R, Mobashery S, Chang M. Lee M, et al. Among authors: chang m. Chem Biol Drug Des. 2009 Feb;73(2):189-202. doi: 10.1111/j.1747-0285.2008.00750.x. Chem Biol Drug Des. 2009. PMID: 19207421 Free PMC article.

7

Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors.

Gooyit M, Lee M, Hesek D, Boggess B, Oliver AG, Fridman R, Mobashery S, Chang M. Gooyit M, et al. Among authors: chang m. Chem Biol Drug Des. 2009 Dec;74(6):535-46. doi: 10.1111/j.1747-0285.2009.00898.x. Epub 2009 Oct 12. Chem Biol Drug Des. 2009. PMID: 19824893 Free PMC article.

8

Endogenous matrix metalloproteinases 2 and 9 regulate activation of CD4+ and CD8+ T cells.

Benson HL, Mobashery S, Chang M, Kheradmand F, Hong JS, Smith GN, Shilling RA, Wilkes DS. Benson HL, et al. Among authors: chang m. Am J Respir Cell Mol Biol. 2011 May;44(5):700-8. doi: 10.1165/rcmb.2010-0125OC. Epub 2010 Jul 16. Am J Respir Cell Mol Biol. 2011. PMID: 20639459 Free PMC article.

9

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases.

Testero SA, Bouley R, Fisher JF, Chang M, Mobashery S. Testero SA, et al. Among authors: chang m. Bioorg Med Chem Lett. 2011 May 1;21(9):2675-8. doi: 10.1016/j.bmcl.2010.12.076. Epub 2010 Dec 29. Bioorg Med Chem Lett. 2011. PMID: 21256011 Free PMC article.

10

Selective water-soluble gelatinase inhibitor prodrugs.

Gooyit M, Lee M, Schroeder VA, Ikejiri M, Suckow MA, Mobashery S, Chang M. Gooyit M, et al. Among authors: chang m. J Med Chem. 2011 Oct 13;54(19):6676-90. doi: 10.1021/jm200566e. Epub 2011 Sep 6. J Med Chem. 2011. PMID: 21866961 Free PMC article.

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