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Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.
Lee MH, Su WP, Wang WJ, Lin SR, Lu CY, Chen YA, Chang JY, Huang SS, Chou PY, Ye SR, Chen SJ, He H, Liu TH, Chou YT, Hsu LJ, Lai FJ, Chen SJ, Lee HC, Kakhniashvili D, Goodman SR, Chang NS. Lee MH, et al. Among authors: chang jy, chang ns. Oncotarget. 2015 Feb 28;6(6):3737-51. doi: 10.18632/oncotarget.2895. Oncotarget. 2015. PMID: 25686832 Free PMC article.
Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation.
Lee MH, Shih YH, Lin SR, Chang JY, Lin YH, Sze CI, Kuo YM, Chang NS. Lee MH, et al. Among authors: chang jy, chang ns. Alzheimers Dement (N Y). 2017 Mar 6;3(2):189-204. doi: 10.1016/j.trci.2017.02.001. eCollection 2017 Jun. Alzheimers Dement (N Y). 2017. PMID: 29067327 Free PMC article.
Therapeutic Zfra4-10 or WWOX7-21 Peptide Induces Complex Formation of WWOX with Selective Protein Targets in Organs that Leads to Cancer Suppression and Spleen Cytotoxic Memory Z Cell Activation In Vivo.
Su WP, Wang WJ, Chang JY, Ho PC, Liu TY, Wen KY, Kuo HL, Chen YJ, Huang SS, Subhan D, Chen YA, Lu CY, Wu CY, Lin SR, Lee MH, Chiang MF, Sze CI, Chang NS. Su WP, et al. Among authors: chang jy, chang ns. Cancers (Basel). 2020 Aug 5;12(8):2189. doi: 10.3390/cancers12082189. Cancers (Basel). 2020. PMID: 32764489 Free PMC article.
1,745 results