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Serial single-cell genomics reveals convergent subclonal evolution of resistance as early-stage breast cancer patients progress on endocrine plus CDK4/6 therapy.
Griffiths JI, Chen J, Cosgrove PA, O'Dea A, Sharma P, Ma C, Trivedi M, Kalinsky K, Wisinski KB, O'Regan R, Makhoul I, Spring LM, Bardia A, Adler FR, Cohen AL, Chang JT, Khan QJ, Bild AH. Griffiths JI, et al. Among authors: chang jt. Nat Cancer. 2021 Jun;2(6):658-671. doi: 10.1038/s43018-021-00215-7. Epub 2021 Jun 3. Nat Cancer. 2021. PMID: 34712959 Free PMC article.
Oncogenic pathway signatures in human cancers as a guide to targeted therapies.
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, Joshi MB, Harpole D, Lancaster JM, Berchuck A, Olson JA Jr, Marks JR, Dressman HK, West M, Nevins JR. Bild AH, et al. Among authors: chang jt. Nature. 2006 Jan 19;439(7074):353-7. doi: 10.1038/nature04296. Epub 2005 Nov 6. Nature. 2006. PMID: 16273092
A pharmacogenomic method for individualized prediction of drug sensitivity.
Cohen AL, Soldi R, Zhang H, Gustafson AM, Wilcox R, Welm BE, Chang JT, Johnson E, Spira A, Jeffrey SS, Bild AH. Cohen AL, et al. Among authors: chang jt. Mol Syst Biol. 2011 Jul 19;7:513. doi: 10.1038/msb.2011.47. Mol Syst Biol. 2011. PMID: 21772261 Free PMC article.
A field guide to genomics research.
Bild AH, Chang JT, Johnson WE, Piccolo SR. Bild AH, et al. Among authors: chang jt. PLoS Biol. 2014 Jan;12(1):e1001744. doi: 10.1371/journal.pbio.1001744. Epub 2014 Jan 7. PLoS Biol. 2014. PMID: 24409093 Free PMC article.
Opportunities for improving cancer treatment using systems biology.
Griffiths JI, Cohen AL, Jones V, Salgia R, Chang JT, Bild AH. Griffiths JI, et al. Among authors: chang jt. Curr Opin Syst Biol. 2019 Oct;17:41-50. doi: 10.1016/j.coisb.2019.10.018. Epub 2019 Nov 27. Curr Opin Syst Biol. 2019. PMID: 32518857 Free PMC article.
Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy.
Griffiths JI, Wallet P, Pflieger LT, Stenehjem D, Liu X, Cosgrove PA, Leggett NA, McQuerry JA, Shrestha G, Rossetti M, Sunga G, Moos PJ, Adler FR, Chang JT, Sharma S, Bild AH. Griffiths JI, et al. Among authors: chang jt. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16072-16082. doi: 10.1073/pnas.1918937117. Epub 2020 Jun 22. Proc Natl Acad Sci U S A. 2020. PMID: 32571915 Free PMC article.
718 results