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The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication.
Hou P, Wang X, Wang H, Wang T, Yu Z, Xu C, Zhao Y, Wang W, Zhao Y, Chu F, Chang H, Zhu H, Lu J, Zhang F, Liang X, Li X, Wang S, Gao Y, He H. Hou P, et al. Among authors: chang h. Autophagy. 2023 Feb;19(2):551-569. doi: 10.1080/15548627.2022.2084686. Epub 2022 Jun 19. Autophagy. 2023. PMID: 35670302 Free PMC article.
Colorectal cancer-specific IFNβ delivery overcomes dysfunctional dsRNA-mediated type I interferon signaling to increase the abscopal effect of radiotherapy.
Huang KC, Chiang SF, Chang HY, Hong WZ, Chen JY, Lee PC, Liang JA, Ke TW, Peng SL, Shiau AC, Chen TW, Yang PC, Chen WT, Chao KSC. Huang KC, et al. Among authors: chang hy. J Immunother Cancer. 2024 May 15;12(5):e008515. doi: 10.1136/jitc-2023-008515. J Immunother Cancer. 2024. PMID: 38749537 Free article.
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