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Computational models in the service of X-ray and cryo-electron microscopy structure determination.
Kryshtafovych A, Moult J, Albrecht R, Chang GA, Chao K, Fraser A, Greenfield J, Hartmann MD, Herzberg O, Josts I, Leiman PG, Linden SB, Lupas AN, Nelson DC, Rees SD, Shang X, Sokolova ML, Tidow H; AlphaFold2 team. Kryshtafovych A, et al. Among authors: chang ga. Proteins. 2021 Dec;89(12):1633-1646. doi: 10.1002/prot.26223. Epub 2021 Sep 6. Proteins. 2021. PMID: 34449113 Free PMC article.
Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating.
Maity K, Heumann JM, McGrath AP, Kopcho NJ, Hsu PK, Lee CW, Mapes JH, Garza D, Krishnan S, Morgan GP, Hendargo KJ, Klose T, Rees SD, Medrano-Soto A, Saier MH Jr, Piñeros M, Komives EA, Schroeder JI, Chang G, Stowell MHB. Maity K, et al. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14309-14318. doi: 10.1073/pnas.1900774116. Epub 2019 Jun 21. Proc Natl Acad Sci U S A. 2019. PMID: 31227607 Free PMC article.
Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Kalogriopoulos NA, Rees SD, Ngo T, Kopcho NJ, Ilatovskiy AV, Sun N, Komives EA, Chang G, Ghosh P, Kufareva I. Kalogriopoulos NA, et al. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16394-16403. doi: 10.1073/pnas.1906658116. Epub 2019 Jul 30. Proc Natl Acad Sci U S A. 2019. PMID: 31363053 Free PMC article.
X-ray structure of EmrE supports dual topology model.
Chen YJ, Pornillos O, Lieu S, Ma C, Chen AP, Chang G. Chen YJ, et al. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18999-9004. doi: 10.1073/pnas.0709387104. Epub 2007 Nov 16. Proc Natl Acad Sci U S A. 2007. PMID: 18024586 Free PMC article.
54 results