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Imbalanced gut microbiota predicts and drives the progression of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in a fast-food diet mouse model.
Fei N, Miyoshi S, Hermanson JB, Miyoshi J, Xie B, DeLeon O, Hawkins M, Charlton W, D'Souza M, Hart J, Sulakhe D, Martinez-Guryn KB, Chang EB, Charlton MR, Leone VA. Fei N, et al. Among authors: chang eb. bioRxiv [Preprint]. 2023 Jan 9:2023.01.09.523249. doi: 10.1101/2023.01.09.523249. bioRxiv. 2023. PMID: 36712061 Free PMC article. Preprint.
Gut microbes and the liver circadian clock partition glucose and lipid metabolism.
Frazier K, Manzoor S, Carroll K, DeLeon O, Miyoshi S, Miyoshi J, St George M, Tan A, Chrisler EA, Izumo M, Takahashi JS, Rao MC, Leone VA, Chang EB. Frazier K, et al. Among authors: chang eb. J Clin Invest. 2023 Sep 15;133(18):e162515. doi: 10.1172/JCI162515. J Clin Invest. 2023. PMID: 37712426 Free PMC article.
Antibiotic-Induced Gut Microbiota Dysbiosis Modulates Host Transcriptome and m6A Epitranscriptome via Bile Acid Metabolism.
Yang M, Zheng X, Fan J, Cheng W, Yan TM, Lai Y, Zhang N, Lu Y, Qi J, Huo Z, Xu Z, Huang J, Jiao Y, Liu B, Pang R, Zhong X, Huang S, Luo GZ, Lee G, Jobin C, Eren AM, Chang EB, Wei H, Pan T, Wang X. Yang M, et al. Among authors: chang eb. Adv Sci (Weinh). 2024 May 7:e2307981. doi: 10.1002/advs.202307981. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38713722
Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis.
Zhang JY, Xiao J, Xie B, Barba H, Boachie-Mensah M, Shah RN, Nadeem U, Spedale M, Dylla N, Lin H, Sidebottom AM, D'Souza M, Theriault B, Sulakhe D, Chang EB, Skondra D. Zhang JY, et al. Among authors: chang eb. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):21. doi: 10.1167/iovs.64.15.21. Invest Ophthalmol Vis Sci. 2023. PMID: 38108689 Free PMC article.
Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
Bosch ME, Dodiya HB, Michalkiewicz J, Lee C, Shaik SM, Weigle IQ, Zhang C, Osborn J, Nambiar A, Patel P, Parhizkar S, Zhang X, Laury ML, Mondal P, Gomm A, Schipma MJ, Mallah D, Butovsky O, Chang EB, Tanzi RE, Gilbert JA, Holtzman DM, Sisodia SS. Bosch ME, et al. Among authors: chang eb. Mol Neurodegener. 2024 Feb 17;19(1):18. doi: 10.1186/s13024-023-00700-w. Mol Neurodegener. 2024. PMID: 38365827 Free PMC article.
A cryptic plasmid is among the most numerous genetic elements in the human gut.
Fogarty EC, Schechter MS, Lolans K, Sheahan ML, Veseli I, Moore RM, Kiefl E, Moody T, Rice PA, Yu MK, Mimee M, Chang EB, Ruscheweyh HJ, Sunagawa S, Mclellan SL, Willis AD, Comstock LE, Eren AM. Fogarty EC, et al. Among authors: chang eb. Cell. 2024 Feb 29;187(5):1206-1222.e16. doi: 10.1016/j.cell.2024.01.039. Cell. 2024. PMID: 38428395 Free article.
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