Chang CW - Search Results

1

Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents.

Liou JP, Chang CW, Song JS, Yang YN, Yeh CF, Tseng HY, Lo YK, Chang YL, Chang CM, Hsieh HP. Liou JP, et al. Among authors: chang cw, chang yl, chang cm. J Med Chem. 2002 Jun 6;45(12):2556-62. doi: 10.1021/jm010365+. J Med Chem. 2002. PMID: 12036364

2

Structure-activity and crystallographic analysis of benzophenone derivatives-the potential anticancer agents.

Hsieh HP, Liou JP, Lin YT, Mahindroo N, Chang JY, Yang YN, Chern SS, Tan UK, Chang CW, Chen TW, Lin CH, Chang YY, Wang CC. Hsieh HP, et al. Among authors: chang cw, chang yy, chang jy. Bioorg Med Chem Lett. 2003 Jan 6;13(1):101-5. doi: 10.1016/s0960-894x(02)00850-8. Bioorg Med Chem Lett. 2003. PMID: 12467626

3

Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents.

Liou JP, Chang JY, Chang CW, Chang CY, Mahindroo N, Kuo FM, Hsieh HP. Liou JP, et al. Among authors: chang cw, chang jy, chang cy. J Med Chem. 2004 May 20;47(11):2897-905. doi: 10.1021/jm0305974. J Med Chem. 2004. PMID: 15139768

4

Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents.

Liou JP, Chang YL, Kuo FM, Chang CW, Tseng HY, Wang CC, Yang YN, Chang JY, Lee SJ, Hsieh HP. Liou JP, et al. Among authors: chang cw, chang yl, chang jy. J Med Chem. 2004 Aug 12;47(17):4247-57. doi: 10.1021/jm049802l. J Med Chem. 2004. PMID: 15293996

5

Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents.

Liou JP, Mahindroo N, Chang CW, Guo FM, Lee SW, Tan UK, Yeh TK, Kuo CC, Chang YW, Lu PH, Tung YS, Lin KT, Chang JY, Hsieh HP. Liou JP, et al. Among authors: chang cw, chang jy, chang yw. ChemMedChem. 2006 Oct;1(10):1106-18. doi: 10.1002/cmdc.200600125. ChemMedChem. 2006. PMID: 16952120

6

Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives.

Yeh JY, Coumar MS, Horng JT, Shiao HY, Kuo FM, Lee HL, Chen IC, Chang CW, Tang WF, Tseng SN, Chen CJ, Shih SR, Hsu JT, Liao CC, Chao YS, Hsieh HP. Yeh JY, et al. Among authors: chang cw. J Med Chem. 2010 Feb 25;53(4):1519-33. doi: 10.1021/jm901570x. J Med Chem. 2010. PMID: 20092255

7

Scaffold-hopping strategy: synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents.

Tung YS, Coumar MS, Wu YS, Shiao HY, Chang JY, Liou JP, Shukla P, Chang CW, Chang CY, Kuo CC, Yeh TK, Lin CY, Wu JS, Wu SY, Liao CC, Hsieh HP. Tung YS, et al. Among authors: chang cw, chang jy, chang cy. J Med Chem. 2011 Apr 28;54(8):3076-80. doi: 10.1021/jm101027s. Epub 2011 Mar 24. J Med Chem. 2011. PMID: 21434659

8

Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system.

Hwang DR, Wu YS, Chang CW, Lien TW, Chen WC, Tan UK, Hsu JT, Hsieh HP. Hwang DR, et al. Among authors: chang cw. Bioorg Med Chem. 2006 Jan 1;14(1):83-91. doi: 10.1016/j.bmc.2005.07.055. Epub 2005 Sep 2. Bioorg Med Chem. 2006. PMID: 16140536

9

Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine Aurora kinase inhibitor.

Shiao HY, Coumar MS, Chang CW, Ke YY, Chi YH, Chu CY, Sun HY, Chen CH, Lin WH, Fung KS, Kuo PC, Huang CT, Chang KY, Lu CT, Hsu JT, Chen CT, Jiaang WT, Chao YS, Hsieh HP. Shiao HY, et al. Among authors: chang cw, chang ky. J Med Chem. 2013 Jul 11;56(13):5247-60. doi: 10.1021/jm4006059. Epub 2013 Jun 28. J Med Chem. 2013. PMID: 23808327

10

3D-QSAR-assisted drug design: identification of a potent quinazoline-based Aurora kinase inhibitor.

Ke YY, Shiao HY, Hsu YC, Chu CY, Wang WC, Lee YC, Lin WH, Chen CH, Hsu JT, Chang CW, Lin CW, Yeh TK, Chao YS, Coumar MS, Hsieh HP. Ke YY, et al. Among authors: chang cw. ChemMedChem. 2013 Jan;8(1):136-48. doi: 10.1002/cmdc.201200464. Epub 2012 Nov 22. ChemMedChem. 2013. PMID: 23172777

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