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Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation.
Zhou S, Szczesna K, Ochalek A, Kobolák J, Varga E, Nemes C, Chandrasekaran A, Rasmussen M, Cirera S, Hyttel P, Dinnyés A, Freude KK, Avci HX. Zhou S, et al. Among authors: chandrasekaran a. Stem Cells Int. 2016;2016:4937689. doi: 10.1155/2016/4937689. Epub 2015 Dec 21. Stem Cells Int. 2016. PMID: 26798357 Free PMC article.
Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism.
Nagy J, Kobolák J, Berzsenyi S, Ábrahám Z, Avci HX, Bock I, Bekes Z, Hodoscsek B, Chandrasekaran A, Téglási A, Dezső P, Koványi B, Vörös ET, Fodor L, Szél T, Németh K, Balázs A, Dinnyés A, Lendvai B, Lévay G, Román V. Nagy J, et al. Among authors: chandrasekaran a. Transl Psychiatry. 2017 Jul 25;7(7):e1179. doi: 10.1038/tp.2017.144. Transl Psychiatry. 2017. PMID: 28742076 Free PMC article.
Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells.
Chandrasekaran A, Avci HX, Ochalek A, Rösingh LN, Molnár K, László L, Bellák T, Téglási A, Pesti K, Mike A, Phanthong P, Bíró O, Hall V, Kitiyanant N, Krause KH, Kobolák J, Dinnyés A. Chandrasekaran A, et al. Stem Cell Res. 2017 Dec;25:139-151. doi: 10.1016/j.scr.2017.10.010. Epub 2017 Oct 14. Stem Cell Res. 2017. PMID: 29128818 Free article.
Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
Ochalek A, Mihalik B, Avci HX, Chandrasekaran A, Téglási A, Bock I, Giudice ML, Táncos Z, Molnár K, László L, Nielsen JE, Holst B, Freude K, Hyttel P, Kobolák J, Dinnyés A. Ochalek A, et al. Among authors: chandrasekaran a. Alzheimers Res Ther. 2017 Dec 1;9(1):90. doi: 10.1186/s13195-017-0317-z. Alzheimers Res Ther. 2017. PMID: 29191219 Free PMC article.
Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.
Chandrasekaran A, Dittlau KS, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TT, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D, Gorodkin J, Muddashetty RS, Meyer M, Aldana BI, Freude KK. Chandrasekaran A, et al. Stem Cell Reports. 2021 Nov 9;16(11):2736-2751. doi: 10.1016/j.stemcr.2021.09.013. Epub 2021 Oct 21. Stem Cell Reports. 2021. PMID: 34678206 Free PMC article.
Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer's disease neurons.
Haukedal H, Corsi GI, Gadekar VP, Doncheva NT, Kedia S, de Haan N, Chandrasekaran A, Jensen P, Schiønning P, Vallin S, Marlet FR, Poon A, Pires C, Agha FK, Wandall HH, Cirera S, Simonsen AH, Nielsen TT, Nielsen JE, Hyttel P, Muddashetty R, Aldana BI, Gorodkin J, Nair D, Meyer M, Larsen MR, Freude K. Haukedal H, et al. Among authors: chandrasekaran a. Front Neurosci. 2023 Feb 16;17:1120086. doi: 10.3389/fnins.2023.1120086. eCollection 2023. Front Neurosci. 2023. PMID: 36875643 Free PMC article.
442 results