Chandler RJ - Search Results

1

ImmTOR nanoparticles enhance AAV transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia.

Ilyinskii PO, Michaud AM, Rizzo GL, Roy CJ, Leung SS, Elkins SL, Capela T, Chowdhury A, Li L, Chandler RJ, Manoli I, Andres-Mateos E, Johnston LPM, Vandenberghe LH, Venditti CP, Kishimoto TK. Ilyinskii PO, et al. Among authors: chandler rj. Mol Ther Methods Clin Dev. 2021 Jul 16;22:279-292. doi: 10.1016/j.omtm.2021.06.015. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34485611 Free PMC article.

2

Genetic and genomic systems to study methylmalonic acidemia.

Chandler RJ, Venditti CP. Chandler RJ, et al. Mol Genet Metab. 2005 Sep-Oct;86(1-2):34-43. doi: 10.1016/j.ymgme.2005.07.020. Epub 2005 Sep 22. Mol Genet Metab. 2005. PMID: 16182581 Free PMC article. Review.

3

Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism.

Chandler RJ, Aswani V, Tsai MS, Falk M, Wehrli N, Stabler S, Allen R, Sedensky M, Kazazian HH, Venditti CP. Chandler RJ, et al. Mol Genet Metab. 2006 Sep-Oct;89(1-2):64-73. doi: 10.1016/j.ymgme.2006.06.001. Epub 2006 Jul 14. Mol Genet Metab. 2006. PMID: 16843692 Free PMC article.

4

Adenoviral-mediated correction of methylmalonyl-CoA mutase deficiency in murine fibroblasts and human hepatocytes.

Chandler RJ, Tsai MS, Dorko K, Sloan J, Korson M, Freeman R, Strom S, Venditti CP. Chandler RJ, et al. BMC Med Genet. 2007 Apr 30;8:24. doi: 10.1186/1471-2350-8-24. BMC Med Genet. 2007. PMID: 17470278 Free PMC article.

5

Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle.

Chandler RJ, Sloan J, Fu H, Tsai M, Stabler S, Allen R, Kaestner KH, Kazazian HH, Venditti CP. Chandler RJ, et al. BMC Med Genet. 2007 Oct 15;8:64. doi: 10.1186/1471-2350-8-64. BMC Med Genet. 2007. PMID: 17937813 Free PMC article.

6

Adenovirus-mediated gene delivery rescues a neonatal lethal murine model of mut(0) methylmalonic acidemia.

Chandler RJ, Venditti CP. Chandler RJ, et al. Hum Gene Ther. 2008 Jan;19(1):53-60. doi: 10.1089/hum.2007.0118. Hum Gene Ther. 2008. PMID: 18052792 Free PMC article.

7

Mitochondrial dysfunction in mut methylmalonic acidemia.

Chandler RJ, Zerfas PM, Shanske S, Sloan J, Hoffmann V, DiMauro S, Venditti CP. Chandler RJ, et al. FASEB J. 2009 Apr;23(4):1252-61. doi: 10.1096/fj.08-121848. Epub 2008 Dec 16. FASEB J. 2009. PMID: 19088183 Free PMC article.

8

Long-term rescue of a lethal murine model of methylmalonic acidemia using adeno-associated viral gene therapy.

Chandler RJ, Venditti CP. Chandler RJ, et al. Mol Ther. 2010 Jan;18(1):11-6. doi: 10.1038/mt.2009.247. Epub 2009 Oct 27. Mol Ther. 2010. PMID: 19861951 Free PMC article.

9

Ion-abrasion scanning electron microscopy reveals distorted liver mitochondrial morphology in murine methylmalonic acidemia.

Murphy GE, Lowekamp BC, Zerfas PM, Chandler RJ, Narasimha R, Venditti CP, Subramaniam S. Murphy GE, et al. Among authors: chandler rj. J Struct Biol. 2010 Aug;171(2):125-32. doi: 10.1016/j.jsb.2010.04.005. Epub 2010 Apr 23. J Struct Biol. 2010. PMID: 20399866 Free PMC article.

10

Liver-directed recombinant adeno-associated viral gene delivery rescues a lethal mouse model of methylmalonic acidemia and provides long-term phenotypic correction.

Carrillo-Carrasco N, Chandler RJ, Chandrasekaran S, Venditti CP. Carrillo-Carrasco N, et al. Among authors: chandler rj. Hum Gene Ther. 2010 Sep;21(9):1147-54. doi: 10.1089/hum.2010.008. Hum Gene Ther. 2010. PMID: 20486773 Free PMC article.

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