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Transcriptional reprogramming of infiltrating neutrophils drives lung pathology in severe COVID-19 despite low viral load.
Eddins DJ, Yang J, Kosters A, Giacalone VD, Pechuan-Jorge X, Chandler JD, Eum J, Babcock BR, Dobosh BS, Hernández MR, Abdulkhader F, Collins GL, Orlova DY, Ramonell RP, Sanz I, Moussion C, Eun-Hyung Lee F, Tirouvanziam RM, Ghosn EEB. Eddins DJ, et al. Among authors: chandler jd. Blood Adv. 2023 Mar 14;7(5):778-799. doi: 10.1182/bloodadvances.2022008834. Blood Adv. 2023. PMID: 36399523 Free PMC article.
Inactivation of SARS-CoV-2 and COVID-19 Patient Samples for Contemporary Immunology and Metabolomics Studies.
Eddins DJ, Bassit LC, Chandler JD, Haddad NS, Musall KL, Yang J, Kosters A, Dobosh BS, Hernández MR, Ramonell RP, Tirouvanziam RM, Lee FE, Zandi K, Schinazi RF, Ghosn EEB. Eddins DJ, et al. Among authors: chandler jd. Immunohorizons. 2022 Feb 16;6(2):144-155. doi: 10.4049/immunohorizons.2200005. Immunohorizons. 2022. PMID: 35173021 Free PMC article.
Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease.
Margaroli C, Horati H, Garratt LW, Giacalone VD, Schofield C, Dittrich AS, Rosenow T, Dobosh BS, Lim HS, Frey DL, Veltman M, Silva GL, Brown MR, Schultz C, Tiddens HAWM, Ranganathan S, Chandler JD, Qiu P, Peng L, Scholte BJ, Mall MA, Kicic A, Guglani L, Stick SM, Janssens HM, Tirouvanziam R. Margaroli C, et al. Among authors: chandler jd. J Cyst Fibros. 2022 Nov;21(6):967-976. doi: 10.1016/j.jcf.2022.06.001. Epub 2022 Jun 19. J Cyst Fibros. 2022. PMID: 35732550 Free article.
Immunometabolic Analysis of Synovial Fluid from Juvenile Idiopathic Arthritis Patients.
Giacalone VD, Cammarata-Mouchtouris A, Moncada-Giraldo D, Shenoy SPV, Ponder LA, Gergely TR, Kim SO, Chandler JD, Vega-Fernandez P, Manos CK, Flanagan ER, Prahalad S, Tirouvanziam R. Giacalone VD, et al. Among authors: chandler jd. Immunohorizons. 2022 Nov 1;6(11):768-778. doi: 10.4049/immunohorizons.2200052. Immunohorizons. 2022. PMID: 36445361 Free article.
Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19.
Druzak S, Iffrig E, Roberts BR, Zhang T, Fibben KS, Sakurai Y, Verkerke HP, Rostad CA, Chahroudi A, Schneider F, Wong AKH, Roberts AM, Chandler JD, Kim SO, Mosunjac M, Mosunjac M, Geller R, Albizua I, Stowell SR, Arthur CM, Anderson EJ, Ivanova AA, Ahn J, Liu X, Maner-Smith K, Bowen T, Paiardini M, Bosinger SE, Roback JD, Kulpa DA, Silvestri G, Lam WA, Ortlund EA, Maier CL. Druzak S, et al. Among authors: chandler jd. Nat Commun. 2023 Apr 4;14(1):1638. doi: 10.1038/s41467-023-37269-3. Nat Commun. 2023. PMID: 37015925 Free PMC article.
Substrate-dependent metabolomic signatures of myeloperoxidase activity in airway epithelial cells: Implications for early cystic fibrosis lung disease.
Kim SO, Shapiro JP, Cottrill KA, Collins GL, Shanthikumar S, Rao P, Ranganathan S, Stick SM, Orr ML, Fitzpatrick AM, Go YM, Jones DP, Tirouvanziam RM, Chandler JD. Kim SO, et al. Among authors: chandler jd. Free Radic Biol Med. 2023 Sep;206:180-190. doi: 10.1016/j.freeradbiomed.2023.06.021. Epub 2023 Jun 23. Free Radic Biol Med. 2023. PMID: 37356776 Free article.
Key inflammatory markers in bronchoalveolar lavage predict bronchiectasis progression in young children with CF.
Horati H, Margaroli C, Chandler JD, Kilgore MB, Manai B, Andrinopoulou ER, Peng L, Guglani L, Tiddens HAMW, Caudri D, Scholte BJ, Tirouvanziam R, Janssens H. Horati H, et al. Among authors: chandler jd. J Cyst Fibros. 2024 Jan 20:S1569-1993(24)00002-X. doi: 10.1016/j.jcf.2024.01.002. Online ahead of print. J Cyst Fibros. 2024. PMID: 38246828 Free article.
60 results