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RNA G-quadruplexes (rG4s): genomics and biological functions.
Lyu K, Chow EY, Mou X, Chan TF, Kwok CK. Lyu K, et al. Among authors: chan tf. Nucleic Acids Res. 2021 Jun 4;49(10):5426-5450. doi: 10.1093/nar/gkab187. Nucleic Acids Res. 2021. PMID: 33772593 Free PMC article. Review.
rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments.
Chow EY, Lyu K, Kwok CK, Chan TF. Chow EY, et al. Among authors: chan tf. RNA Biol. 2020 Jul;17(7):903-917. doi: 10.1080/15476286.2020.1740470. Epub 2020 Apr 26. RNA Biol. 2020. PMID: 32338139 Free PMC article.
We applied these findings to develop a novel bioinformatics pipeline named rG4-seeker (https://github.com/TF-Chan-Lab/rG4-seeker), which uses tailored noise models to autonomously assess and optimize rG4 detections in a replicate-independent manner. ...
We applied these findings to develop a novel bioinformatics pipeline named rG4-seeker (https://github.com/TF-Chan-Lab/rG4-seek …
OMTools: a software package for visualizing and processing optical mapping data.
Leung AK, Jin N, Yip KY, Chan TF. Leung AK, et al. Among authors: chan tf. Bioinformatics. 2017 Sep 15;33(18):2933-2935. doi: 10.1093/bioinformatics/btx317. Bioinformatics. 2017. PMID: 28505226 Free PMC article.
OMTools can be downloaded from https://github.com/aldenleung/OMTools and run on any standard desktop computer equipped with a Java virtual machine. CONTACT: kevinyip@cse.cuhk.edu.hk or tf.chan@cuhk.edu.hk. SUPPLEMENTARY INFORMATION: Supplementary data are available …
OMTools can be downloaded from https://github.com/aldenleung/OMTools and run on any standard desktop computer equipped with a Java virtual m …
344 results