Chan T - Search Results

1

Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System^® (RTS^®) gene switch as gene therapy for the treatment of glioma.

Barrett JA, Cai H, Miao J, Khare PD, Gonzalez P, Dalsing-Hernandez J, Sharma G, Chan T, Cooper LJN, Lebel F. Barrett JA, et al. Among authors: chan t. Cancer Gene Ther. 2018 Jun;25(5-6):106-116. doi: 10.1038/s41417-018-0019-0. Epub 2018 May 14. Cancer Gene Ther. 2018. PMID: 29755109 Free PMC article.

2

Adenovirus-mediated CD40 ligand gene-engineered dendritic cells elicit enhanced CD8(+) cytotoxic T-cell activation and antitumor immunity.

Liu Y, Zhang X, Zhang W, Chen Z, Chan T, Ali K, Jia Z, Xiang J. Liu Y, et al. Among authors: chan t. Cancer Gene Ther. 2002 Feb;9(2):202-8. doi: 10.1038/sj.cgt.7700429. Cancer Gene Ther. 2002. PMID: 11857039

3

HER-2/neu-gene engineered dendritic cell vaccine stimulates stronger HER-2/neu-specific immune responses compared to DNA vaccination.

Chan T, Sami A, El-Gayed A, Guo X, Xiang J. Chan T, et al. Gene Ther. 2006 Oct;13(19):1391-402. doi: 10.1038/sj.gt.3302797. Epub 2006 May 25. Gene Ther. 2006. PMID: 16724093

4

Engineered CD8+ cytotoxic T cells with fiber-modified adenovirus-mediated TNF-alpha gene transfection counteract immunosuppressive interleukin-10-secreting lung metastasis and solid tumors.

Ye Z, Shi M, Chan T, Sas S, Xu S, Xiang J. Ye Z, et al. Among authors: chan t. Cancer Gene Ther. 2007 Jul;14(7):661-75. doi: 10.1038/sj.cgt.7701039. Epub 2007 May 4. Cancer Gene Ther. 2007. PMID: 17479109

5

Vaccination of fiber-modified adenovirus-transfected dendritic cells to express HER-2/neu stimulates efficient HER-2/neu-specific humoral and CTL responses and reduces breast carcinogenesis in transgenic mice.

Sas S, Chan T, Sami A, El-Gayed A, Xiang J. Sas S, et al. Among authors: chan t. Cancer Gene Ther. 2008 Oct;15(10):655-66. doi: 10.1038/cgt.2008.18. Epub 2008 Apr 18. Cancer Gene Ther. 2008. PMID: 18421311

6

Enhanced T-cell immunity induced by dendritic cells with phagocytosis of heat shock protein 70 gene-transfected tumor cells in early phase of apoptosis.

Chan T, Chen Z, Hao S, Xu S, Yuan J, Saxena A, Qureshi M, Zheng C, Xiang J. Chan T, et al. Cancer Gene Ther. 2007 Apr;14(4):409-20. doi: 10.1038/sj.cgt.7701025. Epub 2007 Jan 19. Cancer Gene Ther. 2007. PMID: 17235354

7

Implications for gene therapy-limiting expression of IL-2R gamma c delineate differences in signaling thresholds required for lymphocyte development and maintenance.

Orr SJ, Roessler S, Quigley L, Chan T, Ford JW, O'Connor GM, McVicar DW. Orr SJ, et al. Among authors: chan t. J Immunol. 2010 Aug 1;185(3):1393-403. doi: 10.4049/jimmunol.0903528. Epub 2010 Jun 30. J Immunol. 2010. PMID: 20592278 Free PMC article.

8

Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8⁺ T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice.

Chen Y, Xie Y, Chan T, Sami A, Ahmed S, Liu Q, Xiang J. Chen Y, et al. Among authors: chan t. Cancer Gene Ther. 2011 Jul;18(7):489-99. doi: 10.1038/cgt.2011.18. Epub 2011 May 13. Cancer Gene Ther. 2011. PMID: 21566669 Free PMC article.

9

Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.

Funamizu N, Hu C, Lacy C, Schetter A, Zhang G, He P, Gaedcke J, Ghadimi MB, Ried T, Yfantis HG, Lee DH, Subleski J, Chan T, Weiss JM, Back TC, Yanaga K, Hanna N, Alexander HR, Maitra A, Hussain SP. Funamizu N, et al. Among authors: chan t. Int J Cancer. 2013 Feb 15;132(4):785-94. doi: 10.1002/ijc.27736. Int J Cancer. 2013. PMID: 22821831 Free PMC article.

10

mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment.

Jiang Q, Weiss JM, Back T, Chan T, Ortaldo JR, Guichard S, Wiltrout RH. Jiang Q, et al. Among authors: chan t. Cancer Res. 2011 Jun 15;71(12):4074-84. doi: 10.1158/0008-5472.CAN-10-3968. Epub 2011 May 3. Cancer Res. 2011. PMID: 21540234 Free PMC article.

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