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Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY. White K, et al. Among authors: chan sy. EMBO Mol Med. 2015 Jun;7(6):695-713. doi: 10.15252/emmm.201404511. EMBO Mol Med. 2015. PMID: 25825391 Free PMC article.
Pathogenic mechanisms of pulmonary arterial hypertension.
Chan SY, Loscalzo J. Chan SY, et al. J Mol Cell Cardiol. 2008 Jan;44(1):14-30. doi: 10.1016/j.yjmcc.2007.09.006. Epub 2007 Sep 20. J Mol Cell Cardiol. 2008. PMID: 17950310 Free PMC article. Review.
MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach.
Parikh VN, Jin RC, Rabello S, Gulbahce N, White K, Hale A, Cottrill KA, Shaik RS, Waxman AB, Zhang YY, Maron BA, Hartner JC, Fujiwara Y, Orkin SH, Haley KJ, Barabási AL, Loscalzo J, Chan SY. Parikh VN, et al. Among authors: chan sy. Circulation. 2012 Mar 27;125(12):1520-32. doi: 10.1161/CIRCULATIONAHA.111.060269. Epub 2012 Feb 27. Circulation. 2012. PMID: 22371328 Free PMC article.
Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension.
Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA. Maron BA, et al. Among authors: chan sy. Circulation. 2012 Aug 21;126(8):963-74. doi: 10.1161/CIRCULATIONAHA.112.094722. Epub 2012 Jul 11. Circulation. 2012. PMID: 22787113 Free PMC article.
1,075 results