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Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release.
Marchand A, Winther AM, Holm PJ, Olesen C, Montigny C, Arnou B, Champeil P, Clausen JD, Vilsen B, Andersen JP, Nissen P, Jaxel C, Møller JV, le Maire M. Marchand A, et al. Among authors: champeil p. J Biol Chem. 2008 May 23;283(21):14867-82. doi: 10.1074/jbc.M710165200. Epub 2008 Mar 20. J Biol Chem. 2008. PMID: 18356161 Free article.
A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate.
Azouaoui H, Montigny C, Ash MR, Fijalkowski F, Jacquot A, Grønberg C, López-Marqués RL, Palmgren MG, Garrigos M, le Maire M, Decottignies P, Gourdon P, Nissen P, Champeil P, Lenoir G. Azouaoui H, et al. Among authors: champeil p. PLoS One. 2014 Nov 13;9(11):e112176. doi: 10.1371/journal.pone.0112176. eCollection 2014. PLoS One. 2014. PMID: 25393116 Free PMC article.
High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N- and C-terminal extensions.
Azouaoui H, Montigny C, Dieudonné T, Champeil P, Jacquot A, Vázquez-Ibar JL, Le Maréchal P, Ulstrup J, Ash MR, Lyons JA, Nissen P, Lenoir G. Azouaoui H, et al. Among authors: champeil p. J Biol Chem. 2017 May 12;292(19):7954-7970. doi: 10.1074/jbc.M116.751487. Epub 2017 Mar 16. J Biol Chem. 2017. PMID: 28302728 Free PMC article.
100 results