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APOEε4 potentiates amyloid β effects on longitudinal tau pathology.
Ferrari-Souza JP, Bellaver B, Ferreira PCL, Benedet AL, Povala G, Lussier FZ, Leffa DT, Therriault J, Tissot C, Soares C, Wang YT, Chamoun M, Servaes S, Macedo AC, Vermeiren M, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, Cohen A, Lopez OL, Klunk WE, Soucy JP, Gauthier S, Souza DO, Triana-Baltzer G, Saad ZS, Kolb HC, Karikari TK, Villemagne VL, Tudorascu DL, Ashton NJ, Zetterberg H, Blennow K, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: chamoun m. Nat Aging. 2023 Oct;3(10):1210-1218. doi: 10.1038/s43587-023-00490-2. Epub 2023 Sep 25. Nat Aging. 2023. PMID: 37749258 Free PMC article.
In vivo quantification of neurofibrillary tangles with [18F]MK-6240.
Pascoal TA, Shin M, Kang MS, Chamoun M, Chartrand D, Mathotaarachchi S, Bennacef I, Therriault J, Ng KP, Hopewell R, Bouhachi R, Hsiao HH, Benedet AL, Soucy JP, Massarweh G, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Among authors: chamoun m. Alzheimers Res Ther. 2018 Jul 31;10(1):74. doi: 10.1186/s13195-018-0402-y. Alzheimers Res Ther. 2018. PMID: 30064520 Free PMC article.
Aβ-induced vulnerability propagates via the brain's default mode network.
Pascoal TA, Mathotaarachchi S, Kang MS, Mohaddes S, Shin M, Park AY, Parent MJ, Benedet AL, Chamoun M, Therriault J, Hwang H, Cuello AC, Misic B, Soucy JP, Aston JAD, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Among authors: chamoun m. Nat Commun. 2019 Jun 4;10(1):2353. doi: 10.1038/s41467-019-10217-w. Nat Commun. 2019. PMID: 31164641 Free PMC article.
Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive individuals.
Benedet AL, Ashton NJ, Pascoal TA, Leuzy A, Mathotaarachchi S, Kang MS, Therriault J, Savard M, Chamoun M, Schöll M, Zimmer ER, Gauthier S, Labbe A, Zetterberg H, Blennow K, Neto PR. Benedet AL, et al. Among authors: chamoun m. Alzheimers Dement (Amst). 2019 Sep 27;11:679-689. doi: 10.1016/j.dadm.2019.08.002. eCollection 2019 Dec. Alzheimers Dement (Amst). 2019. PMID: 31673598 Free PMC article.
Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Chamoun M, Savard M, Thomas E, Kang MS, Lussier F, Tissot C, Parsons M, Qureshi MNI, Vitali P, Massarweh G, Soucy JP, Rej S, Saha-Chaudhuri P, Gauthier S, Rosa-Neto P. Therriault J, et al. Among authors: chamoun m. JAMA Neurol. 2020 Apr 1;77(4):470-479. doi: 10.1001/jamaneurol.2019.4421. JAMA Neurol. 2020. PMID: 31860000 Free PMC article.
Mild behavioral impairment is associated with β-amyloid but not tau or neurodegeneration in cognitively intact elderly individuals.
Lussier FZ, Pascoal TA, Chamoun M, Therriault J, Tissot C, Savard M, Kang MS, Mathotaarachchi S, Benedet AL, Parsons M, Qureshi MNI, Thomas ÉM, Shin M, Dion LA, Massarweh G, Soucy JP, Tsai IH, Vitali P, Ismail Z, Rosa-Neto P, Gauthier S. Lussier FZ, et al. Among authors: chamoun m. Alzheimers Dement. 2020 Jan;16(1):192-199. doi: 10.1002/alz.12007. Alzheimers Dement. 2020. PMID: 31914223 Free PMC article.
APOEε4 potentiates the relationship between amyloid-β and tau pathologies.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Savard M, Chamoun M, Thomas E, Kang MS, Lussier F, Tissot C, Soucy JP, Massarweh G, Rej S, Saha-Chaudhuri P, Poirier J, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Therriault J, et al. Among authors: chamoun m. Mol Psychiatry. 2021 Oct;26(10):5977-5988. doi: 10.1038/s41380-020-0688-6. Epub 2020 Mar 11. Mol Psychiatry. 2021. PMID: 32161362 Free PMC article.
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts.
Karikari TK, Pascoal TA, Ashton NJ, Janelidze S, Benedet AL, Rodriguez JL, Chamoun M, Savard M, Kang MS, Therriault J, Schöll M, Massarweh G, Soucy JP, Höglund K, Brinkmalm G, Mattsson N, Palmqvist S, Gauthier S, Stomrud E, Zetterberg H, Hansson O, Rosa-Neto P, Blennow K. Karikari TK, et al. Among authors: chamoun m. Lancet Neurol. 2020 May;19(5):422-433. doi: 10.1016/S1474-4422(20)30071-5. Lancet Neurol. 2020. PMID: 32333900
Topographical distribution of Aβ predicts progression to dementia in Aβ positive mild cognitive impairment.
Pascoal TA, Therriault J, Mathotaarachchi S, Kang MS, Shin M, Benedet AL, Chamoun M, Tissot C, Lussier F, Mohaddes S, Soucy JP, Massarweh G, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Pascoal TA, et al. Among authors: chamoun m. Alzheimers Dement (Amst). 2020 Jun 21;12(1):e12037. doi: 10.1002/dad2.12037. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 32582834 Free PMC article.
Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer's disease.
Kang MS, Aliaga AA, Shin M, Mathotaarachchi S, Benedet AL, Pascoal TA, Therriault J, Chamoun M, Savard M, Devenyi GA, Mathieu A, Chakravarty MM, Sandelius Å, Blennow K, Zetterberg H, Soucy JP, Cuello AC, Massarweh G, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Kang MS, et al. Among authors: chamoun m. Mol Psychiatry. 2021 Oct;26(10):5989-6001. doi: 10.1038/s41380-020-0818-1. Epub 2020 Jun 26. Mol Psychiatry. 2021. PMID: 32591633 Free PMC article.
71 results