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Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer.
Tapia-Galisteo A, Sánchez Rodríguez Í, Aguilar-Sopeña O, Harwood SL, Narbona J, Ferreras Gutierrez M, Navarro R, Martín-García L, Corbacho C, Compte M, Lacadena J, Blanco FJ, Chames P, Roda-Navarro P, Álvarez-Vallina L, Sanz L. Tapia-Galisteo A, et al. Among authors: chames p. Oncoimmunology. 2022 Feb 7;11(1):2034355. doi: 10.1080/2162402X.2022.2034355. eCollection 2022. Oncoimmunology. 2022. PMID: 35154908 Free PMC article.
Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-β and PD-L1 enhances antitumor responses.
Tapia-Galisteo A, Sánchez-Rodríguez I, Narbona J, Iglesias-Hernández P, Aragón-García S, Jiménez-Reinoso A, Compte M, Khan S, Tsuda T, Chames P, Lacadena J, Álvarez-Vallina L, Sanz L. Tapia-Galisteo A, et al. Among authors: chames p. Oncoimmunology. 2024 Apr 13;13(1):2338558. doi: 10.1080/2162402X.2024.2338558. eCollection 2024. Oncoimmunology. 2024. PMID: 38623463 Free PMC article.
Single-domain antibody-based and linker-free bispecific antibodies targeting FcγRIII induce potent antitumor activity without recruiting regulatory T cells.
Rozan C, Cornillon A, Pétiard C, Chartier M, Behar G, Boix C, Kerfelec B, Robert B, Pèlegrin A, Chames P, Teillaud JL, Baty D. Rozan C, et al. Among authors: chames p. Mol Cancer Ther. 2013 Aug;12(8):1481-91. doi: 10.1158/1535-7163.MCT-12-1012. Epub 2013 Jun 11. Mol Cancer Ther. 2013. PMID: 23757164
Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets.
Arnould S, Chames P, Perez C, Lacroix E, Duclert A, Epinat JC, Stricher F, Petit AS, Patin A, Guillier S, Rolland S, Prieto J, Blanco FJ, Bravo J, Montoya G, Serrano L, Duchateau P, Pâques F. Arnould S, et al. Among authors: chames p. J Mol Biol. 2006 Jan 20;355(3):443-58. doi: 10.1016/j.jmb.2005.10.065. Epub 2005 Nov 15. J Mol Biol. 2006. PMID: 16310802
Masked selection: a straightforward and flexible approach for the selection of binders against specific epitopes and differentially expressed proteins by phage display.
Even-Desrumeaux K, Nevoltris D, Lavaut MN, Alim K, Borg JP, Audebert S, Kerfelec B, Baty D, Chames P. Even-Desrumeaux K, et al. Among authors: chames p. Mol Cell Proteomics. 2014 Feb;13(2):653-65. doi: 10.1074/mcp.O112.025486. Epub 2013 Dec 20. Mol Cell Proteomics. 2014. PMID: 24361863 Free PMC article.
78 results