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Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant agents.
Boateng ST, Roy T, Torrey K, Owunna U, Banang-Mbeumi S, Basnet D, Niedda E, Alexander AD, Hage DE, Atchimnaidu S, Nagalo BM, Aryal D, Findley A, Seeram NP, Efimova T, Sechi M, Hill RA, Ma H, Chamcheu JC, Murru S. Boateng ST, et al. Among authors: chamcheu jc. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2205042. doi: 10.1080/14756366.2023.2205042. J Enzyme Inhib Med Chem. 2023. PMID: 37184042 Free PMC article.
Multifaceted approach toward mapping out the anticancer properties of small molecules via in vitro evaluation on melanoma and nonmelanoma skin cancer cells, and in silico target fishing.
Boateng ST, Roy T, Agbo ME, Mahmud MA, Banang-Mbeumi S, Chamcheu RN, Yadav RK, Bramwell M, Pham LK, Dang DD, Jackson KE, Nagalo BM, Hill RA, Efimova T, Fotie J, Chamcheu JC. Boateng ST, et al. Among authors: chamcheu jc. Chem Biol Drug Des. 2024 Jan;103(1):e14418. doi: 10.1111/cbdd.14418. Chem Biol Drug Des. 2024. PMID: 38230791
Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers.
Roy T, Boateng ST, Banang-Mbeumi S, Singh PK, Basnet P, Chamcheu RN, Ladu F, Chauvin I, Spiegelman VS, Hill RA, Kousoulas KG, Nagalo BM, Walker AL, Fotie J, Murru S, Sechi M, Chamcheu JC. Roy T, et al. Among authors: chamcheu jc, chamcheu rn. Bioorg Chem. 2021 Feb;107:104595. doi: 10.1016/j.bioorg.2020.104595. Epub 2020 Dec 30. Bioorg Chem. 2021. PMID: 33450548 Free PMC article.
Identification of new fisetin analogs as kinase inhibitors: Data on synthesis and anti-skin cancer activities evaluation.
Roy T, Boateng ST, Banang-Mbeumi S, Singh PK, Basnet P, Chamcheu RN, Ladu F, Chauvin I, Spiegelman VS, Hill RA, Kousoulas KG, Nagalo BM, Walker AL, Fotie J, Murru S, Sechi M, Chamcheu JC. Roy T, et al. Among authors: chamcheu jc, chamcheu rn. Data Brief. 2021 Feb 10;35:106858. doi: 10.1016/j.dib.2021.106858. eCollection 2021 Apr. Data Brief. 2021. PMID: 33665254 Free PMC article.
49 results