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Page 1
Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury.
Kayagaki N, Stowe IB, Alegre K, Deshpande I, Wu S, Lin Z, Kornfeld OS, Lee BL, Zhang J, Liu J, Suto E, Lee WP, Schneider K, Lin W, Seshasayee D, Bhangale T, Chalouni C, Johnson MC, Joshi P, Mossemann J, Zhao S, Ali D, Goldenberg NM, Sayed BA, Steinberg BE, Newton K, Webster JD, Kelly RL, Dixit VM. Kayagaki N, et al. Among authors: chalouni c. Nature. 2023 Jun;618(7967):1072-1077. doi: 10.1038/s41586-023-06191-5. Epub 2023 May 17. Nature. 2023. PMID: 37196676 Free PMC article.
LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity.
Krishnamurty AT, Shyer JA, Thai M, Gandham V, Buechler MB, Yang YA, Pradhan RN, Wang AW, Sanchez PL, Qu Y, Breart B, Chalouni C, Dunlap D, Ziai J, Elstrott J, Zacharias N, Mao W, Rowntree RK, Sadowsky J, Lewis GD, Pillow TH, Nabet BY, Banchereau R, Tam L, Caothien R, Bacarro N, Roose-Girma M, Modrusan Z, Mariathasan S, Müller S, Turley SJ. Krishnamurty AT, et al. Among authors: chalouni c. Nature. 2022 Nov;611(7934):148-154. doi: 10.1038/s41586-022-05272-1. Epub 2022 Sep 28. Nature. 2022. PMID: 36171287 Free PMC article.
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.
Le Thomas A, Ferri E, Marsters S, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z, Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A. Le Thomas A, et al. Among authors: chalouni c. Nat Commun. 2021 Dec 15;12(1):7310. doi: 10.1038/s41467-021-27597-7. Nat Commun. 2021. PMID: 34911951 Free PMC article.
The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology.
Astarita JL, Keerthivasan S, Husain B, Şenbabaoğlu Y, Verschueren E, Gierke S, Pham VC, Peterson SM, Chalouni C, Pierce AA, Lill JR, Gonzalez LC, Martinez-Martin N, Turley SJ. Astarita JL, et al. Among authors: chalouni c. PLoS One. 2021 Dec 8;16(12):e0260800. doi: 10.1371/journal.pone.0260800. eCollection 2021. PLoS One. 2021. PMID: 34879110 Free PMC article.
Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response.
Maculins T, Verschueren E, Hinkle T, Choi M, Chang P, Chalouni C, Rao S, Kwon Y, Lim J, Katakam AK, Kunz RC, Erickson BK, Huang T, Tsai TH, Vitek O, Reichelt M, Senbabaoglu Y, Mckenzie B, Rohde JR, Dikic I, Kirkpatrick DS, Murthy A. Maculins T, et al. Among authors: chalouni c. Elife. 2021 Jun 4;10:e62320. doi: 10.7554/eLife.62320. Elife. 2021. PMID: 34085925 Free PMC article.
Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues.
Kapoor VN, Müller S, Keerthivasan S, Brown M, Chalouni C, Storm EE, Castiglioni A, Lane R, Nitschke M, Dominguez CX, Astarita JL, Krishnamurty AT, Carbone CB, Senbabaoglu Y, Wang AW, Wu X, Cremasco V, Roose-Girma M, Tam L, Doerr J, Chen MZ, Lee WP, Modrusan Z, Yang YA, Bourgon R, Sandoval W, Shaw AS, de Sauvage FJ, Mellman I, Moussion C, Turley SJ. Kapoor VN, et al. Among authors: chalouni c. Nat Immunol. 2021 May;22(5):571-585. doi: 10.1038/s41590-021-00920-6. Epub 2021 Apr 26. Nat Immunol. 2021. PMID: 33903764
Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation.
Nalle SC, Barreira da Silva R, Zhang H, Decker M, Chalouni C, Xu M, Posthuma G, de Mazière A, Klumperman J, Baz Morelli A, Fleire SJ, Verkman AS, Trombetta ES, Albert ML, Mellman I. Nalle SC, et al. Among authors: chalouni c. PLoS One. 2020 Nov 24;15(11):e0238484. doi: 10.1371/journal.pone.0238484. eCollection 2020. PLoS One. 2020. PMID: 33232321 Free PMC article.
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
Guan J, Zhou W, Hafner M, Blake RA, Chalouni C, Chen IP, De Bruyn T, Giltnane JM, Hartman SJ, Heidersbach A, Houtman R, Ingalla E, Kategaya L, Kleinheinz T, Li J, Martin SE, Modrusan Z, Nannini M, Oeh J, Ubhayakar S, Wang X, Wertz IE, Young A, Yu M, Sampath D, Hager JH, Friedman LS, Daemen A, Metcalfe C. Guan J, et al. Among authors: chalouni c. Cell. 2019 Aug 8;178(4):949-963.e18. doi: 10.1016/j.cell.2019.06.026. Epub 2019 Jul 25. Cell. 2019. PMID: 31353221 Free article.
45 results