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Page 1
Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration.
Nunes MJ, Carvalho AN, Reis J, Costa D, Moutinho M, Mateus J, Mendes de Almeida R, Brito S, Risso D, Nunes S, Castro-Caldas M, Gama MJ, Rodrigues CMP, Xapelli S, Diógenes MJ, Cartier N, Chali F, Piguet F, Rodrigues E. Nunes MJ, et al. Among authors: chali f. Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):166993. doi: 10.1016/j.bbadis.2023.166993. Epub 2023 Dec 22. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38142760 Free article.
Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy.
Houdebine L, D'Amico D, Bastin J, Chali F, Desseille C, Rumeau V, Soukkari J, Oudot C, Rouquet T, Bariohay B, Roux J, Sapaly D, Weill L, Lopes P, Djouadi F, Bezier C, Charbonnier F, Biondi O. Houdebine L, et al. Among authors: chali f. Front Physiol. 2019 Oct 1;10:1258. doi: 10.3389/fphys.2019.01258. eCollection 2019. Front Physiol. 2019. PMID: 31632295 Free PMC article.
Microglial phenotypes in the human epileptic temporal lobe.
Morin-Brureau M, Milior G, Royer J, Chali F, Le Duigou C, Savary E, Blugeon C, Jourdren L, Akbar D, Dupont S, Navarro V, Baulac M, Bielle F, Mathon B, Clemenceau S, Miles R. Morin-Brureau M, et al. Among authors: chali f. Brain. 2018 Dec 1;141(12):3343-3360. doi: 10.1093/brain/awy276. Brain. 2018. PMID: 30462183 Free PMC article.
Imaging pathological activities of human brain tissue in organotypic culture.
Le Duigou C, Savary E, Morin-Brureau M, Gomez-Dominguez D, Sobczyk A, Chali F, Milior G, Kraus L, Meier JC, Kullmann DM, Mathon B, de la Prida LM, Dorfmuller G, Pallud J, Eugène E, Clemenceau S, Miles R. Le Duigou C, et al. Among authors: chali f. J Neurosci Methods. 2018 Mar 15;298:33-44. doi: 10.1016/j.jneumeth.2018.02.001. Epub 2018 Feb 7. J Neurosci Methods. 2018. PMID: 29427611 Free PMC article.
Long-term exercise-specific neuroprotection in spinal muscular atrophy-like mice.
Chali F, Desseille C, Houdebine L, Benoit E, Rouquet T, Bariohay B, Lopes P, Branchu J, Della Gaspera B, Pariset C, Chanoine C, Charbonnier F, Biondi O. Chali F, et al. J Physiol. 2016 Apr 1;594(7):1931-52. doi: 10.1113/JP271361. Epub 2016 Feb 27. J Physiol. 2016. PMID: 26915343 Free PMC article.
IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.
Biondi O, Branchu J, Ben Salah A, Houdebine L, Bertin L, Chali F, Desseille C, Weill L, Sanchez G, Lancelin C, Aïd S, Lopes P, Pariset C, Lécolle S, Côté J, Holzenberger M, Chanoine C, Massaad C, Charbonnier F. Biondi O, et al. Among authors: chali f. J Neurosci. 2015 Aug 26;35(34):12063-79. doi: 10.1523/JNEUROSCI.0608-15.2015. J Neurosci. 2015. PMID: 26311784 Free PMC article.
CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.
Djelti F, Braudeau J, Hudry E, Dhenain M, Varin J, Bièche I, Marquer C, Chali F, Ayciriex S, Auzeil N, Alves S, Langui D, Potier MC, Laprevote O, Vidaud M, Duyckaerts C, Miles R, Aubourg P, Cartier N. Djelti F, et al. Among authors: chali f. Brain. 2015 Aug;138(Pt 8):2383-98. doi: 10.1093/brain/awv166. Epub 2015 Jul 2. Brain. 2015. PMID: 26141492
15 results