Chakka S - Search Results

1

MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival.

Lee CS, Lee LC, Yuan TL, Chakka S, Fellmann C, Lowe SW, Caplen NJ, McCormick F, Luo J. Lee CS, et al. Among authors: chakka s. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4508-4517. doi: 10.1073/pnas.1817494116. Epub 2019 Feb 1. Proc Natl Acad Sci U S A. 2019. PMID: 30709910 Free PMC article.

2

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.

Ou O, Huppi K, Chakka S, Gehlhaus K, Dubois W, Patel J, Chen J, Mackiewicz M, Jones TL, Pitt JJ, Martin SE, Goldsmith P, Simmons JK, Mock BA, Caplen NJ. Ou O, et al. Among authors: chakka s. Cancer Lett. 2014 Nov 28;354(2):336-47. doi: 10.1016/j.canlet.2014.08.043. Epub 2014 Sep 1. Cancer Lett. 2014. PMID: 25193464 Free PMC article.

3

Identification of therapeutic targets applicable to clinical strategies in ovarian cancer.

Kim MK, Caplen N, Chakka S, Hernandez L, House C, Pongas G, Jordan E, Annunziata CM. Kim MK, et al. Among authors: chakka s. BMC Cancer. 2016 Aug 24;16(1):678. doi: 10.1186/s12885-016-2675-5. BMC Cancer. 2016. PMID: 27558154 Free PMC article.

4

BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 (HP1).

Pongas G, Kim MK, Min DJ, House CD, Jordan E, Caplen N, Chakka S, Ohiri J, Kruhlak MJ, Annunziata CM. Pongas G, et al. Among authors: chakka s. Oncotarget. 2017 May 3;8(31):51402-51415. doi: 10.18632/oncotarget.17572. eCollection 2017 Aug 1. Oncotarget. 2017. PMID: 28881656 Free PMC article.

5

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening.

Garimella SV, Gehlhaus K, Dine JL, Pitt JJ, Grandin M, Chakka S, Nau MM, Caplen NJ, Lipkowitz S. Garimella SV, et al. Among authors: chakka s. Breast Cancer Res. 2014 Apr 17;16(2):R41. doi: 10.1186/bcr3645. Breast Cancer Res. 2014. PMID: 24745479 Free PMC article.

6

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

Jo U, Murai Y, Chakka S, Chen L, Cheng K, Murai J, Saha LK, Miller Jenkins LM, Pommier Y. Jo U, et al. Among authors: chakka s. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2015654118. doi: 10.1073/pnas.2015654118. Proc Natl Acad Sci U S A. 2021. PMID: 33536335 Free PMC article.

7

SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243.

Murai Y, Jo U, Murai J, Jenkins LM, Huang SN, Chakka S, Chen L, Cheng K, Fukuda S, Takebe N, Pommier Y. Murai Y, et al. Among authors: chakka s. Cancer Res. 2021 Jun 1;81(11):3067-3078. doi: 10.1158/0008-5472.CAN-20-2694. Epub 2021 Apr 16. Cancer Res. 2021. PMID: 33863777 Free PMC article.

8

High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2.

Coussens NP, Kales SC, Henderson MJ, Lee OW, Horiuchi KY, Wang Y, Chen Q, Kuznetsova E, Wu J, Chakka S, Cheff DM, Cheng KC, Shinn P, Brimacombe KR, Shen M, Simeonov A, Lal-Nag M, Ma H, Jadhav A, Hall MD. Coussens NP, et al. Among authors: chakka s. J Biol Chem. 2018 Aug 31;293(35):13750-13765. doi: 10.1074/jbc.RA118.004274. Epub 2018 Jun 26. J Biol Chem. 2018. PMID: 29945974 Free PMC article.

9

Change in disease activity needed for meaningful change in cutaneous lupus by patient characteristic: A retrospective analysis of a longitudinal database.

Kleitsch J, Pandya R, Chakka S, Yan D, Lim D, Diaz D, Feng R, Werth VP. Kleitsch J, et al. Among authors: chakka s. J Am Acad Dermatol. 2024 Feb;90(2):406-408. doi: 10.1016/j.jaad.2023.09.077. Epub 2023 Oct 6. J Am Acad Dermatol. 2024. PMID: 37806526 No abstract available.

10

Mpox virus and coinfections: An approach to rapid diagnosis.

Derrick KM, Marson JW, Chakka S, Heilman ER. Derrick KM, et al. Among authors: chakka s. J Cutan Pathol. 2023 Oct;50(10):878-883. doi: 10.1111/cup.14490. Epub 2023 Jul 9. J Cutan Pathol. 2023. PMID: 37423617

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