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Spatial clustering of CD68+ tumor associated macrophages with tumor cells is associated with worse overall survival in metastatic clear cell renal cell carcinoma.
Chakiryan NH, Kimmel GJ, Kim Y, Hajiran A, Aydin AM, Zemp L, Katende E, Nguyen J, Lopez-Blanco N, Chahoud J, Spiess PE, Fournier M, Dhillon J, Wang L, Moran-Segura C, El-Kenawi A, Mulé J, Altrock PM, Manley BJ. Chakiryan NH, et al. PLoS One. 2021 Apr 21;16(4):e0245415. doi: 10.1371/journal.pone.0245415. eCollection 2021. PLoS One. 2021. PMID: 33882057 Free PMC article.
Geospatial Cellular Distribution of Cancer-Associated Fibroblasts Significantly Impacts Clinical Outcomes in Metastatic Clear Cell Renal Cell Carcinoma.
Chakiryan NH, Kimmel GJ, Kim Y, Johnson JO, Clark N, Hajiran A, Chang A, Aydin AM, Zemp L, Katende E, Chahoud J, Ferrall-Fairbanks MC, Spiess PE, Francis N, Fournier M, Dhillon J, Park JY, Wang L, Mulé JJ, Altrock PM, Manley BJ. Chakiryan NH, et al. Cancers (Basel). 2021 Jul 26;13(15):3743. doi: 10.3390/cancers13153743. Cancers (Basel). 2021. PMID: 34359645 Free PMC article.
Proteogenomic, Epigenetic, and Clinical Implications of Recurrent Aberrant Splice Variants in Clear Cell Renal Cell Carcinoma.
Chang A, Chakiryan NH, Du D, Stewart PA, Zhang Y, Tian Y, Soupir AC, Bowers K, Fang B, Morganti A, Teer JK, Kim Y, Spiess PE, Chahoud J, Noble JD, Putney RM, Berglund AE, Robinson TJ, Koomen JM, Wang L, Manley BJ. Chang A, et al. Among authors: chakiryan nh. Eur Urol. 2022 Oct;82(4):354-362. doi: 10.1016/j.eururo.2022.05.021. Epub 2022 Jun 17. Eur Urol. 2022. PMID: 35718636 Free PMC article.
Geospatial characterization of immune cell distributions and dynamics across the microenvironment in clear cell renal cell carcinoma.
Chakiryan NH, Kim Y, Berglund A, Chang A, Kimmel GJ, Hajiran A, Nguyen J, Moran-Segura C, Saeed-Vafa D, Katende EN, Lopez-Blanco N, Chahoud J, Rappold P, Spiess PE, Fournier M, Jeong D, Wang L, Teer JK, Dhillon J, Kuo F, Hakimi AA, Altrock PM, Mulé JJ, Manley BJ. Chakiryan NH, et al. J Immunother Cancer. 2023 Apr;11(4):e006195. doi: 10.1136/jitc-2022-006195. J Immunother Cancer. 2023. PMID: 37185232 Free PMC article.
Correlating Immune Cell Infiltration Patterns with Recurrent Somatic Mutations in Advanced Clear Cell Renal Cell Carcinoma.
Chakiryan NH, Hajiran A, Kim Y, Aydin AM, Zemp L, Katende E, Nguyen J, Fan W, Cheng CH, Lopez-Blanco N, Chahoud J, Spiess PE, Fournier M, Dhillon J, Wang L, Moran-Segura C, Mulé J, Du D, Yoder SJ, Berglund A, Teer JK, Manley BJ. Chakiryan NH, et al. Eur Urol Focus. 2022 May;8(3):784-793. doi: 10.1016/j.euf.2021.04.014. Epub 2021 May 11. Eur Urol Focus. 2022. PMID: 33994165 Free PMC article.
Quantification of T- and B-cell Immune Receptor Distribution Diversity Characterizes Immune Cell Infiltration and Lymphocyte Heterogeneity in Clear Cell Renal Cell Carcinoma.
Ferrall-Fairbanks MC, Chakiryan NH, Chobrutskiy BI, Kim Y, Teer JK, Berglund A, Mulé JJ, Fournier M, Siegel EM, Dhillon J, Falasiri SSA, Arturo JF, Katende EN, Blanck G, Manley BJ, Altrock PM. Ferrall-Fairbanks MC, et al. Among authors: chakiryan nh. Cancer Res. 2022 Mar 1;82(5):929-942. doi: 10.1158/0008-5472.CAN-21-1747. Cancer Res. 2022. PMID: 35031572 Free PMC article.
Reconnaissance of tumor immune microenvironment spatial heterogeneity in metastatic renal cell carcinoma and correlation with immunotherapy response.
Hajiran A, Chakiryan N, Aydin AM, Zemp L, Nguyen J, Laborde JM, Chahoud J, Spiess PE, Zaman S, Falasiri S, Fournier M, Teer JK, Dhillon J, McCarthy S, Moran-Segura C, Katende EN, Sexton WJ, Koomen JM, Mulé J, Kim Y, Manley B. Hajiran A, et al. Clin Exp Immunol. 2021 Apr;204(1):96-106. doi: 10.1111/cei.13567. Epub 2021 Feb 9. Clin Exp Immunol. 2021. PMID: 33346915 Free PMC article.
42 results