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Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue.
Clin Proteomics. 2023 Oct 25;20(1):47. doi: 10.1186/s12014-023-09435-8.
Clin Proteomics. 2023.
PMID: 37880622
Free PMC article.
Global Extraction from Parallel Reaction Monitoring to Quantify Background Peptides for Improved Normalization and Quality Control in Targeted Proteomics.
Chambers AG, Sweet SMM, Chain D, Kim YJ.
Chambers AG, et al.
Anal Chem. 2021 Oct 12;93(40):13434-13440. doi: 10.1021/acs.analchem.1c01375. Epub 2021 Sep 30.
Anal Chem. 2021.
PMID: 34591457
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The addition of FAIMS increases targeted proteomics sensitivity from FFPE tumor biopsies.
Sweet S, Chain D, Yu W, Martin P, Rebelatto M, Chambers A, Cecchi F, Kim YJ.
Sweet S, et al.
Sci Rep. 2022 Aug 16;12(1):13876. doi: 10.1038/s41598-022-16358-1.
Sci Rep. 2022.
PMID: 35974054
Free PMC article.
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Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.
Zanvit P, van Dyk D, Fazenbaker C, McGlinchey K, Luo W, Pezold JM, Meekin J, Chang CY, Carrasco RA, Breen S, Cheung CS, Endlich-Frazier A, Clark B, Chu NJ, Vantellini A, Martin PL, Hoover CE, Riley K, Sweet SM, Chain D, Kim YJ, Tu E, Harder N, Phipps S, Damschroder M, Gilbreth RN, Cobbold M, Moody G, Bosco EE.
Zanvit P, et al.
J Clin Invest. 2023 Nov 15;133(22):e169655. doi: 10.1172/JCI169655.
J Clin Invest. 2023.
PMID: 37966111
Free PMC article.
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Urinary markers differentially associate with kidney inflammatory activity and chronicity measures in patients with lupus nephritis.
Akhgar A, Sinibaldi D, Zeng L, Farris AB 3rd, Cobb J, Battle M, Chain D, Cann JA, Illei GG, Lim SS, White WI.
Akhgar A, et al.
Lupus Sci Med. 2023 Jan;10(1):e000747. doi: 10.1136/lupus-2022-000747.
Lupus Sci Med. 2023.
PMID: 36717181
Free PMC article.
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The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice.
Pang Z, Wu NN, Zhao W, Chain DC, Schaffer E, Zhang X, Yamdagni P, Palejwala VA, Fan C, Favara SG, Dressler HM, Economides KD, Weinstock D, Cavallo JS, Naimi S, Galzin AM, Guillot E, Pruniaux MP, Tocci MJ, Polites HG.
Pang Z, et al. Among authors: chain dc.
Obesity (Silver Spring). 2011 Oct;19(10):1923-34. doi: 10.1038/oby.2011.250. Epub 2011 Jul 28.
Obesity (Silver Spring). 2011.
PMID: 21799481
Free article.
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