Chaikuad A - Search Results

1

DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.

Strubel A, Münick P, Hartmann O, Chaikuad A, Dreier B, Schaefer JV, Gebel J, Osterburg C, Tuppi M, Schäfer B, Buck V, Rosenfeldt M, Knapp S, Plückthun A, Diefenbacher ME, Dötsch V. Strubel A, et al. Among authors: chaikuad a. Cell Death Dis. 2023 Oct 12;14(10):674. doi: 10.1038/s41419-023-06213-0. Cell Death Dis. 2023. PMID: 37828008 Free PMC article.

2

UDP-glucose dehydrogenase: structure and function of a potential drug target.

Egger S, Chaikuad A, Kavanagh KL, Oppermann U, Nidetzky B. Egger S, et al. Among authors: chaikuad a. Biochem Soc Trans. 2010 Oct;38(5):1378-85. doi: 10.1042/BST0381378. Biochem Soc Trans. 2010. PMID: 20863317 Review.

3

Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.

Chaikuad A, Brady RL. Chaikuad A, et al. BMC Struct Biol. 2009 Jul 3;9:42. doi: 10.1186/1472-6807-9-42. BMC Struct Biol. 2009. PMID: 19575810 Free PMC article.

4

Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

Egger S, Chaikuad A, Klimacek M, Kavanagh KL, Oppermann U, Nidetzky B. Egger S, et al. Among authors: chaikuad a. J Biol Chem. 2012 Jan 13;287(3):2119-29. doi: 10.1074/jbc.M111.313015. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22123821 Free PMC article.

5

Structural comparison of human mammalian ste20-like kinases.

Record CJ, Chaikuad A, Rellos P, Das S, Pike AC, Fedorov O, Marsden BD, Knapp S, Lee WH. Record CJ, et al. Among authors: chaikuad a. PLoS One. 2010 Aug 6;5(8):e11905. doi: 10.1371/journal.pone.0011905. PLoS One. 2010. PMID: 20730082 Free PMC article.

6

A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics.

Chaikuad A, Tacconi EM, Zimmer J, Liang Y, Gray NS, Tarsounas M, Knapp S. Chaikuad A, et al. Nat Chem Biol. 2014 Oct;10(10):853-60. doi: 10.1038/nchembio.1629. Epub 2014 Sep 7. Nat Chem Biol. 2014. PMID: 25195011 Free PMC article.

7

Defined PEG smears as an alternative approach to enhance the search for crystallization conditions and crystal-quality improvement in reduced screens.

Chaikuad A, Knapp S, von Delft F. Chaikuad A, et al. Acta Crystallogr D Biol Crystallogr. 2015 Aug;71(Pt 8):1627-39. doi: 10.1107/S1399004715007968. Epub 2015 Jul 28. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26249344 Free PMC article.

8

The ins and outs of selective kinase inhibitor development.

Müller S, Chaikuad A, Gray NS, Knapp S. Müller S, et al. Among authors: chaikuad a. Nat Chem Biol. 2015 Nov;11(11):818-21. doi: 10.1038/nchembio.1938. Nat Chem Biol. 2015. PMID: 26485069 No abstract available.

9

Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.

Chaikuad A, Lang S, Brennan PE, Temperini C, Fedorov O, Hollander J, Nachane R, Abell C, Müller S, Siegal G, Knapp S. Chaikuad A, et al. J Med Chem. 2016 Feb 25;59(4):1648-53. doi: 10.1021/acs.jmedchem.5b01719. Epub 2016 Jan 13. J Med Chem. 2016. PMID: 26731131 Free PMC article.

10

Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors.

Lavogina D, Kestav K, Chaikuad A, Heroven C, Knapp S, Uri A. Lavogina D, et al. Among authors: chaikuad a. Acta Crystallogr F Struct Biol Commun. 2016 May;72(Pt 5):339-45. doi: 10.1107/S2053230X16004611. Epub 2016 Apr 22. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27139824 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

120 results

Search Page