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KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity.
Costanzo-Garvey DL, Pfluger PT, Dougherty MK, Stock JL, Boehm M, Chaika O, Fernandez MR, Fisher K, Kortum RL, Hong EG, Jun JY, Ko HJ, Schreiner A, Volle DJ, Treece T, Swift AL, Winer M, Chen D, Wu M, Leon LR, Shaw AS, McNeish J, Kim JK, Morrison DK, Tschöp MH, Lewis RE. Costanzo-Garvey DL, et al. Among authors: chaika o. Cell Metab. 2009 Nov;10(5):366-78. doi: 10.1016/j.cmet.2009.09.010. Cell Metab. 2009. PMID: 19883615 Free PMC article.
The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis.
Kortum RL, Costanzo DL, Haferbier J, Schreiner SJ, Razidlo GL, Wu MH, Volle DJ, Mori T, Sakaue H, Chaika NV, Chaika OV, Lewis RE. Kortum RL, et al. Among authors: chaika ov. Mol Cell Biol. 2005 Sep;25(17):7592-604. doi: 10.1128/MCB.25.17.7592-7604.2005. Mol Cell Biol. 2005. PMID: 16107706 Free PMC article.
Anti-apoptotic signaling by a colony-stimulating factor-1 receptor/insulin receptor chimera with a juxtamembrane deletion.
Boehm JE, Chaika OV, Lewis RE. Boehm JE, et al. Among authors: chaika ov. J Biol Chem. 1998 Mar 20;273(12):7169-76. doi: 10.1074/jbc.273.12.7169. J Biol Chem. 1998. PMID: 9507032 Free article.
CSF-1-treated cells expressing the CSF1R/IRDelta960 are unable to phosphorylate IRS-1 and Shc (Chaika, O. V., Chaika, N., Volle, D. J., Wilden, P. A. , Pirrucello, S. ...
CSF-1-treated cells expressing the CSF1R/IRDelta960 are unable to phosphorylate IRS-1 and Shc (Chaika, O. V., Chaika, N …
Rac-dependent anti-apoptotic signaling by the insulin receptor cytoplasmic domain.
Boehm JE, Chaika OV, Lewis RE. Boehm JE, et al. Among authors: chaika ov. J Biol Chem. 1999 Oct 1;274(40):28632-6. doi: 10.1074/jbc.274.40.28632. J Biol Chem. 1999. PMID: 10497231 Free article.
Mutations in the cytoplasmic domain of the insulin receptor that block the ability of the receptor to stimulate glucose uptake do not block the receptor's ability to inhibit apoptosis (Boehm, J. E., Chaika, O. V., and Lewis, R. E. (1998) J. Biol. Chem. 273, 7169-717 …
Mutations in the cytoplasmic domain of the insulin receptor that block the ability of the receptor to stimulate glucose uptake do not block …
31 results