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98 results

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Page 1
Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD.
Hristova VA, Watson A, Chaerkady R, Glover MS, Ackland J, Angerman B, Belfield G, Belvisi MG, Burke H, Cellura D, Clark HW, Etal D, Freeman A, Heinson AI, Hess S, Hühn M, Hall E, Mackay A, Madsen J, McCrae C, Muthas D, Novick S, Ostridge K, Öberg L, Platt A, Postle AD, Spalluto CM, Vaarala O, Wang J, Staples KJ, Wilkinson TMA; MICA II Study group. Hristova VA, et al. Among authors: chaerkady r. ERJ Open Res. 2022 May 15;9(3):00378-2022. doi: 10.1183/23120541.00378-2022. eCollection 2023 May. ERJ Open Res. 2022. PMID: 37228288 Free PMC article.
A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation.
Fletcher A, Clift D, de Vries E, Martinez Cuesta S, Malcolm T, Meghini F, Chaerkady R, Wang J, Chiang A, Weng SHS, Tart J, Wong E, Donohoe G, Rawlins P, Gordon E, Taylor JD, James L, Hunt J. Fletcher A, et al. Among authors: chaerkady r. Nat Commun. 2023 Nov 4;14(1):7093. doi: 10.1038/s41467-023-42546-2. Nat Commun. 2023. PMID: 37925433 Free PMC article.
Dysregulation of COVID-19 related gene expression in the COPD lung.
Watson A, Öberg L, Angermann B, Spalluto CM, Hühn M, Burke H, Cellura D, Freeman A, Muthas D, Etal D, Belfield G, Karlsson F, Nordström K, Ostridge K, Staples KJ, Wilkinson T; MICA II Studygroup. Watson A, et al. Respir Res. 2021 May 29;22(1):164. doi: 10.1186/s12931-021-01755-3. Respir Res. 2021. PMID: 34051791 Free PMC article.
Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR.
Mao S, Chaerkady R, Yu W, D'Angelo G, Garcia A, Chen H, Barrett AM, Phipps S, Fleming R, Hess S, Koopmann JO, Dimasi N, Wilson S, Pugh K, Cook K, Masterson LA, Gao C, Wu H, Herbst R, Howard PW, Tice DA, Cobbold M, Harper J. Mao S, et al. Among authors: chaerkady r. Mol Cancer Ther. 2021 Mar;20(3):541-552. doi: 10.1158/1535-7163.MCT-20-0351. Mol Cancer Ther. 2021. PMID: 33653945
Development of a Parallel Reaction Monitoring Mass Spectrometry Assay for the Detection of SARS-CoV-2 Spike Glycoprotein and Nucleoprotein.
Cazares LH, Chaerkady R, Samuel Weng SH, Boo CC, Cimbro R, Hsu HE, Rajan S, Dall'Acqua W, Clarke L, Ren K, McTamney P, Kallewaard-LeLay N, Ghaedi M, Ikeda Y, Hess S. Cazares LH, et al. Among authors: chaerkady r. Anal Chem. 2020 Oct 20;92(20):13813-13821. doi: 10.1021/acs.analchem.0c02288. Epub 2020 Oct 5. Anal Chem. 2020. PMID: 32966064
Proteogenomic Annotation of Chinese Hamsters Reveals Extensive Novel Translation Events and Endogenous Retroviral Elements.
Li S, Cha SW, Heffner K, Hizal DB, Bowen MA, Chaerkady R, Cole RN, Tejwani V, Kaushik P, Henry M, Meleady P, Sharfstein ST, Betenbaugh MJ, Bafna V, Lewis NE. Li S, et al. Among authors: chaerkady r. J Proteome Res. 2019 Jun 7;18(6):2433-2445. doi: 10.1021/acs.jproteome.8b00935. Epub 2019 May 8. J Proteome Res. 2019. PMID: 31020842 Free PMC article.
Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice.
Cohen TS, Takahashi V, Bonnell J, Tovchigrechko A, Chaerkady R, Yu W, Jones-Nelson O, Lee Y, Raja R, Hess S, Stover CK, Worthington JJ, Travis MA, Sellman BR. Cohen TS, et al. Among authors: chaerkady r. J Clin Invest. 2019 Apr 15;129(5):2133-2144. doi: 10.1172/JCI126938. eCollection 2019 Apr 15. J Clin Invest. 2019. PMID: 30985291 Free PMC article.
98 results