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Discovery of novel tetrahydroisoquinoline-containing pyrimidines as ALK inhibitors.
Achary R, Yun JI, Park CM, Mathi GR, Lee JY, Ha JD, Chae CH, Ahn S, Park CH, Lee CO, Hwang JY, Yun CS, Jung HJ, Cho SY, Kim HR, Kim P. Achary R, et al. Among authors: chae ch. Bioorg Med Chem. 2016 Jan 15;24(2):207-19. doi: 10.1016/j.bmc.2015.12.004. Epub 2015 Dec 7. Bioorg Med Chem. 2016. PMID: 26712094
Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitis.
Jung SK, Ko Y, Yu KR, Kim JH, Lee JY, Chae CH, Ji S, Kim CH, Lee HK, Choi EB, Kim BY, Erikson RL, Chung SJ, Kim SJ. Jung SK, et al. Among authors: chae ch. Bioorg Med Chem Lett. 2012 Mar 1;22(5):2084-8. doi: 10.1016/j.bmcl.2012.01.011. Epub 2012 Jan 21. Bioorg Med Chem Lett. 2012. PMID: 22326397
Novel bis-ortho-alkoxy-para-piperazinesubstituted-2,4-dianilinopyrimidines (KRCA-0008) as potent and selective ALK inhibitors for anticancer treatment.
Park CH, Choe H, Jang IY, Kwon SY, Latif M, Lee HK, Lee HJ, Yang EH, Yun JI, Chae CH, Cho SY, Choi SU, Ha JD, Jung H, Kim HR, Kim P, Lee CO, Yun CS, Lee K. Park CH, et al. Among authors: chae ch. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6192-6. doi: 10.1016/j.bmcl.2013.08.090. Epub 2013 Sep 4. Bioorg Med Chem Lett. 2013. PMID: 24095090
86 results