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Dimethyl fumarate is highly cytotoxic in KRAS mutated cancer cells but spares non-tumorigenic cells.
Bennett Saidu NE, Bretagne M, Mansuet AL, Just PA, Leroy K, Cerles O, Chouzenoux S, Nicco C, Damotte D, Alifano M, Borghese B, Goldwasser F, Batteux F, Alexandre J. Bennett Saidu NE, et al. Among authors: cerles o. Oncotarget. 2018 Jan 10;9(10):9088-9099. doi: 10.18632/oncotarget.24144. eCollection 2018 Feb 6. Oncotarget. 2018. PMID: 29507676 Free PMC article.
Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications.
Saidu NE, Noé G, Cerles O, Cabel L, Kavian-Tessler N, Chouzenoux S, Bahuaud M, Chéreau C, Nicco C, Leroy K, Borghese B, Goldwasser F, Batteux F, Alexandre J. Saidu NE, et al. Among authors: cerles o. Mol Cancer Ther. 2017 Mar;16(3):529-539. doi: 10.1158/1535-7163.MCT-16-0405. Epub 2017 Jan 9. Mol Cancer Ther. 2017. PMID: 28069874
Leflunomide prevents ROS-induced systemic fibrosis in mice.
Morin F, Kavian N, Chouzenoux S, Cerles O, Nicco C, Chéreau C, Batteux F. Morin F, et al. Among authors: cerles o. Free Radic Biol Med. 2017 Jul;108:192-203. doi: 10.1016/j.freeradbiomed.2017.03.035. Epub 2017 Mar 30. Free Radic Biol Med. 2017. PMID: 28365359
18 results