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Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
Legru A, Verdirosa F, Vo-Hoang Y, Tassone G, Vascon F, Thomas CA, Sannio F, Corsica G, Benvenuti M, Feller G, Coulon R, Marcoccia F, Devente SR, Bouajila E, Piveteau C, Leroux F, Deprez-Poulain R, Deprez B, Licznar-Fajardo P, Crowder MW, Cendron L, Pozzi C, Mangani S, Docquier JD, Hernandez JF, Gavara L. Legru A, et al. Among authors: cendron l. J Med Chem. 2022 Dec 22;65(24):16392-16419. doi: 10.1021/acs.jmedchem.2c01257. Epub 2022 Nov 30. J Med Chem. 2022. PMID: 36450011 Free article.
Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation.
Nielsen AL, Bognar Z, Mothukuri GK, Zarda A, Schuttel M, Merz ML, Ji X, Will E, Chinellato M, Bartling CRO, Stromgaard K, Cendron L, Angelini A, Heinis C. Nielsen AL, et al. Among authors: cendron l. Angew Chem Int Ed Engl. 2024 Apr 11:e202400350. doi: 10.1002/anie.202400350. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38602024
The protease activated receptor 2 - CCAAT/enhancer-binding protein beta - SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis.
Villano G, Novo E, Turato C, Quarta S, Ruvoletto M, Biasiolo A, Protopapa F, Chinellato M, Martini A, Trevellin E, Granzotto M, Cannito S, Cendron L, De Siervi S, Guido M, Parola M, Vettor R, Pontisso P. Villano G, et al. Among authors: cendron l. Mol Metab. 2024 Mar;81:101889. doi: 10.1016/j.molmet.2024.101889. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307387 Free PMC article.
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies.
Marchesan E, Nardin A, Mauri S, Bernardo G, Chander V, Di Paola S, Chinellato M, von Stockum S, Chakraborty J, Herkenne S, Basso V, Schrepfer E, Marin O, Cendron L, Medina DL, Scorrano L, Ziviani E. Marchesan E, et al. Among authors: cendron l. Cell Death Differ. 2024 Feb;31(2):217-238. doi: 10.1038/s41418-023-01251-9. Epub 2024 Jan 18. Cell Death Differ. 2024. PMID: 38238520 Free PMC article.
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria.
Bersani M, Failla M, Vascon F, Gianquinto E, Bertarini L, Baroni M, Cruciani G, Verdirosa F, Sannio F, Docquier JD, Cendron L, Spyrakis F, Lazzarato L, Tondi D. Bersani M, et al. Among authors: cendron l. Pharmaceuticals (Basel). 2023 Dec 2;16(12):1682. doi: 10.3390/ph16121682. Pharmaceuticals (Basel). 2023. PMID: 38139809 Free PMC article.
In vitro binding analysis of legacy-linear and new generation-cyclic perfluoro-alkyl substances on sex hormone binding globulin and albumin, suggests low impact on serum hormone kinetics of testosterone.
Pavan A, Cendron L, Di Nisio A, Pedrucci F, Sabovic I, Scarso A, Ferlin A, Angelini A, Foresta C, De Toni L. Pavan A, et al. Among authors: cendron l. Toxicology. 2023 Dec;500:153664. doi: 10.1016/j.tox.2023.153664. Epub 2023 Nov 4. Toxicology. 2023. PMID: 37931871 Free article.
95 results